KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXW4
All Species:
27.27
Human Site:
Y397
Identified Species:
66.67
UniProt:
P57775
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57775
NP_071322.1
412
46337
Y397
R
L
T
T
K
H
L
Y
A
A
L
S
Y
N
L
Chimpanzee
Pan troglodytes
XP_507994
575
62275
Y560
R
L
T
T
K
H
L
Y
A
A
L
S
Y
N
L
Rhesus Macaque
Macaca mulatta
XP_001110869
410
46201
Y395
R
L
T
T
K
H
L
Y
A
A
L
S
Y
N
L
Dog
Lupus familis
XP_543981
408
45636
Y393
R
F
T
T
K
H
L
Y
A
A
L
S
Y
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMJ2
410
46123
Y395
R
F
T
T
R
H
L
Y
A
A
L
S
Y
N
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511284
401
44487
V388
Q
E
Q
T
V
T
W
V
I
E
I
G
K
G
R
Chicken
Gallus gallus
XP_001233793
416
46314
Y401
R
F
S
T
T
H
L
Y
A
A
L
A
S
A
L
Frog
Xenopus laevis
NP_001091296
417
47291
Y395
Q
F
N
T
R
H
L
Y
A
A
L
A
S
A
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122354
423
49394
Y381
S
F
D
N
T
Y
L
Y
G
A
T
D
Q
H
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196990
262
29395
T250
S
G
I
F
R
A
F
T
V
S
V
A
I
P
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.8
98.3
94.9
N.A.
91
N.A.
N.A.
49
68.7
61.1
N.A.
N.A.
N.A.
30.5
N.A.
25.7
Protein Similarity:
100
68.6
98.7
95.8
N.A.
93.9
N.A.
N.A.
61.4
80.2
75.7
N.A.
N.A.
N.A.
46.5
N.A.
39.8
P-Site Identity:
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
6.6
60
53.3
N.A.
N.A.
N.A.
26.6
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
20
73.3
73.3
N.A.
N.A.
N.A.
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
70
80
0
30
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
50
0
10
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
10
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
70
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
10
0
0
0
0
0
10
0
10
0
10
0
0
% I
% Lys:
0
0
0
0
40
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
30
0
0
0
0
80
0
0
0
70
0
0
0
80
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
0
0
0
50
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
20
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
60
0
0
0
30
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
20
0
10
0
0
0
0
0
0
10
0
50
20
0
0
% S
% Thr:
0
0
50
80
20
10
0
10
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
10
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
80
0
0
0
0
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _