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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPPK1 All Species: 15.76
Human Site: T739 Identified Species: 43.33
UniProt: P58107 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P58107 NP_112598.2 5065 553094 T739 L L D P S D D T K G F F D P N
Chimpanzee Pan troglodytes XP_520007 2395 262114 T510 A Q Q Y Q E G T L S V E K L A
Rhesus Macaque Macaca mulatta XP_001088100 2396 262151 A511 A Q Q H Q E G A L S V E K M A
Dog Lupus familis XP_532347 2948 321188 T775 L A D P S D D T K G F F D P N
Cat Felis silvestris
Mouse Mus musculus Q8R0W0 6548 724491 T772 L L D P S D D T K G F F D P N
Rat Rattus norvegicus P30427 4687 533521 E1646 L R R Q V Q D E S Q R K R Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520101 1516 165469
Chicken Gallus gallus XP_427045 2908 320037 T678 L L E A Q A A T R F V I D P A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922664 4120 460268 T728 L N D P T D D T K G F F D P N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.4 44.3 45.2 N.A. 58.5 22.7 N.A. 23.5 33.3 N.A. 42.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 46.8 45.6 51.2 N.A. 66.5 40.1 N.A. 27 44.2 N.A. 58.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 0 93.3 N.A. 100 13.3 N.A. 0 33.3 N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 6.6 93.3 N.A. 100 13.3 N.A. 0 46.6 N.A. 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 12 0 12 0 12 12 12 0 0 0 0 0 0 45 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 45 0 0 45 56 0 0 0 0 0 56 0 0 % D
% Glu: 0 0 12 0 0 23 0 12 0 0 0 23 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 12 45 45 0 0 0 % F
% Gly: 0 0 0 0 0 0 23 0 0 45 0 0 0 0 0 % G
% His: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 45 0 0 12 23 0 0 % K
% Leu: 67 34 0 0 0 0 0 0 23 0 0 0 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % M
% Asn: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 45 % N
% Pro: 0 0 0 45 0 0 0 0 0 0 0 0 0 56 0 % P
% Gln: 0 23 23 12 34 12 0 0 0 12 0 0 0 12 0 % Q
% Arg: 0 12 12 0 0 0 0 0 12 0 12 0 12 0 0 % R
% Ser: 0 0 0 0 34 0 0 0 12 23 0 0 0 0 0 % S
% Thr: 0 0 0 0 12 0 0 67 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 12 0 0 0 0 0 34 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _