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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROK1
All Species:
31.82
Human Site:
S64
Identified Species:
87.5
UniProt:
P58294
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58294
NP_115790.1
105
11715
S64
G
E
E
C
H
P
G
S
H
K
V
P
F
F
R
Chimpanzee
Pan troglodytes
XP_001141562
129
14197
T72
G
D
S
C
H
P
L
T
R
K
N
N
F
G
S
Rhesus Macaque
Macaca mulatta
XP_001101188
105
11706
S64
G
E
E
C
H
P
G
S
H
K
V
P
F
F
R
Dog
Lupus familis
XP_547234
105
11620
S64
G
E
E
C
H
P
G
S
H
K
V
P
F
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q14A28
105
11659
S64
G
E
E
C
H
P
G
S
H
K
I
P
F
L
R
Rat
Rattus norvegicus
Q8R414
105
11624
S64
G
E
E
C
H
P
G
S
H
K
I
P
F
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508430
230
24832
S189
G
D
E
C
H
P
V
S
H
K
V
P
F
F
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001091325
111
12178
S68
G
D
D
C
H
P
L
S
H
K
I
P
Y
F
G
Zebra Danio
Brachydanio rerio
NP_001099168
105
11744
S64
G
D
E
C
H
P
Y
S
H
K
V
P
F
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.4
96.1
89.5
N.A.
84.7
89.5
N.A.
40
N.A.
51.3
64.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
56.5
97.1
93.3
N.A.
90.4
95.2
N.A.
43
N.A.
66.6
79
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
100
100
N.A.
86.6
93.3
N.A.
80
N.A.
60
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
100
100
N.A.
93.3
100
N.A.
86.6
N.A.
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
45
12
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
56
78
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
89
67
0
% F
% Gly:
100
0
0
0
0
0
56
0
0
0
0
0
0
12
34
% G
% His:
0
0
0
0
100
0
0
0
89
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
23
0
0
0
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
0
% N
% Pro:
0
0
0
0
0
100
0
0
0
0
0
89
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
56
% R
% Ser:
0
0
12
0
0
0
0
89
0
0
0
0
0
0
12
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
12
0
0
0
56
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _