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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLF1
All Species:
31.21
Human Site:
S147
Identified Species:
68.67
UniProt:
P58340
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58340
NP_001123629.1
268
30627
S147
T
R
K
A
M
R
D
S
D
S
G
L
E
K
M
Chimpanzee
Pan troglodytes
XP_516842
268
30670
S147
T
R
K
A
M
R
D
S
D
S
G
L
E
K
M
Rhesus Macaque
Macaca mulatta
XP_001102054
267
30586
S146
T
R
K
A
M
R
D
S
D
S
G
L
E
K
M
Dog
Lupus familis
XP_534319
303
34306
S180
T
R
R
A
L
R
D
S
D
S
G
L
E
K
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9QWV4
267
30413
S147
T
R
K
A
M
R
D
S
D
S
G
L
E
R
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508090
246
27769
G132
G
L
E
K
M
A
V
G
H
H
I
H
D
R
A
Chicken
Gallus gallus
XP_422822
275
31455
S154
T
R
K
A
L
K
D
S
E
S
G
V
E
K
M
Frog
Xenopus laevis
NP_001088844
245
27988
T131
P
A
K
V
F
Q
S
T
S
Q
T
S
R
A
P
Zebra Danio
Brachydanio rerio
NP_001020687
250
28397
D136
E
T
R
Q
T
M
R
D
S
Q
S
G
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NKV0
376
41359
S144
T
R
R
T
V
Q
D
S
R
T
G
V
K
K
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796343
284
31913
S147
T
R
K
T
V
R
D
S
A
Q
G
I
E
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
67
N.A.
79.8
N.A.
N.A.
60.4
55.2
49.6
38
N.A.
25.7
N.A.
N.A.
35.5
Protein Similarity:
100
99.2
96.6
76.2
N.A.
90.3
N.A.
N.A.
73.8
71.6
66
53.3
N.A.
38
N.A.
N.A.
54.2
P-Site Identity:
100
100
100
86.6
N.A.
93.3
N.A.
N.A.
6.6
73.3
6.6
0
N.A.
46.6
N.A.
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
26.6
100
20
13.3
N.A.
86.6
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
55
0
10
0
0
10
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
73
10
46
0
0
0
10
0
0
% D
% Glu:
10
0
10
0
0
0
0
0
10
0
0
0
64
10
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
0
0
73
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% I
% Lys:
0
0
64
10
0
10
0
0
0
0
0
0
10
64
0
% K
% Leu:
0
10
0
0
19
0
0
0
0
0
0
46
10
0
0
% L
% Met:
0
0
0
0
46
10
0
0
0
0
0
0
0
0
73
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
10
0
19
0
0
0
28
0
0
0
0
0
% Q
% Arg:
0
73
28
0
0
55
10
0
10
0
0
0
10
19
10
% R
% Ser:
0
0
0
0
0
0
10
73
19
55
10
10
0
0
0
% S
% Thr:
73
10
0
19
10
0
0
10
0
10
10
0
0
0
0
% T
% Val:
0
0
0
10
19
0
10
0
0
0
0
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _