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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLF1
All Species:
21.52
Human Site:
S170
Identified Species:
47.33
UniProt:
P58340
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58340
NP_001123629.1
268
30627
S170
R
A
H
V
I
K
K
S
K
N
K
K
T
G
D
Chimpanzee
Pan troglodytes
XP_516842
268
30670
S170
R
A
H
V
I
K
K
S
K
N
K
K
T
G
D
Rhesus Macaque
Macaca mulatta
XP_001102054
267
30586
S169
R
A
H
V
I
K
K
S
K
N
R
K
T
G
D
Dog
Lupus familis
XP_534319
303
34306
N205
H
V
I
K
K
S
K
N
N
K
T
G
D
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QWV4
267
30413
S170
R
G
H
V
I
R
K
S
K
N
N
K
T
G
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508090
246
27769
K149
I
K
K
S
K
N
N
K
T
G
E
Q
E
V
N
Chicken
Gallus gallus
XP_422822
275
31455
S177
R
A
H
V
V
K
K
S
K
N
R
K
T
G
D
Frog
Xenopus laevis
NP_001088844
245
27988
I148
I
K
E
T
K
K
A
I
R
D
S
E
S
G
I
Zebra Danio
Brachydanio rerio
NP_001020687
250
28397
R153
I
G
H
H
I
G
E
R
G
H
V
M
E
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NKV0
376
41359
E167
R
A
H
I
I
E
K
E
Q
D
M
R
S
G
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796343
284
31913
S170
R
G
H
V
I
E
K
S
K
N
T
R
T
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
67
N.A.
79.8
N.A.
N.A.
60.4
55.2
49.6
38
N.A.
25.7
N.A.
N.A.
35.5
Protein Similarity:
100
99.2
96.6
76.2
N.A.
90.3
N.A.
N.A.
73.8
71.6
66
53.3
N.A.
38
N.A.
N.A.
54.2
P-Site Identity:
100
100
93.3
6.6
N.A.
80
N.A.
N.A.
0
86.6
13.3
13.3
N.A.
40
N.A.
N.A.
73.3
P-Site Similarity:
100
100
100
20
N.A.
86.6
N.A.
N.A.
20
100
40
26.6
N.A.
80
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
19
0
0
10
0
55
% D
% Glu:
0
0
10
0
0
19
10
10
0
0
10
10
19
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
28
0
0
0
10
0
0
10
10
0
10
0
73
0
% G
% His:
10
0
73
10
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
28
0
10
10
64
0
0
10
0
0
0
0
0
0
10
% I
% Lys:
0
19
10
10
28
46
73
10
55
10
19
46
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
10
10
55
10
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
10
% Q
% Arg:
64
0
0
0
0
10
0
10
10
0
19
19
0
10
0
% R
% Ser:
0
0
0
10
0
10
0
55
0
0
10
0
19
0
10
% S
% Thr:
0
0
0
10
0
0
0
0
10
0
19
0
55
0
0
% T
% Val:
0
10
0
55
10
0
0
0
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _