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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLF1
All Species:
13.33
Human Site:
S45
Identified Species:
29.33
UniProt:
P58340
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58340
NP_001123629.1
268
30627
S45
G
R
D
L
L
S
I
S
D
G
R
G
R
A
H
Chimpanzee
Pan troglodytes
XP_516842
268
30670
S45
G
R
D
L
L
S
I
S
D
G
R
G
R
A
H
Rhesus Macaque
Macaca mulatta
XP_001102054
267
30586
P45
G
R
D
L
L
S
I
P
D
G
R
G
R
A
R
Dog
Lupus familis
XP_534319
303
34306
S64
G
R
D
L
L
S
I
S
D
G
R
R
Q
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QWV4
267
30413
S45
G
R
D
L
L
S
I
S
D
G
R
G
R
T
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508090
246
27769
D33
T
R
N
Q
K
G
R
D
N
S
E
V
A
L
H
Chicken
Gallus gallus
XP_422822
275
31455
I45
G
R
D
P
F
L
S
I
T
D
G
R
E
R
T
Frog
Xenopus laevis
NP_001088844
245
27988
S32
H
V
R
Q
M
M
R
S
F
S
D
P
F
G
R
Zebra Danio
Brachydanio rerio
NP_001020687
250
28397
F37
G
S
F
G
M
D
P
F
A
L
T
P
Q
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NKV0
376
41359
P45
R
L
M
N
S
F
M
P
D
P
F
M
Q
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796343
284
31913
A45
Q
F
M
P
S
I
E
A
R
G
V
R
R
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
67
N.A.
79.8
N.A.
N.A.
60.4
55.2
49.6
38
N.A.
25.7
N.A.
N.A.
35.5
Protein Similarity:
100
99.2
96.6
76.2
N.A.
90.3
N.A.
N.A.
73.8
71.6
66
53.3
N.A.
38
N.A.
N.A.
54.2
P-Site Identity:
100
100
86.6
80
N.A.
93.3
N.A.
N.A.
13.3
20
6.6
6.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
86.6
86.6
N.A.
93.3
N.A.
N.A.
26.6
20
13.3
20
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
10
0
0
0
10
37
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
55
0
0
10
0
10
55
10
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% E
% Phe:
0
10
10
0
10
10
0
10
10
0
10
0
10
0
0
% F
% Gly:
64
0
0
10
0
10
0
0
0
55
10
37
0
10
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
37
% H
% Ile:
0
0
0
0
0
10
46
10
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
46
46
10
0
0
0
10
0
0
0
10
0
% L
% Met:
0
0
19
0
19
10
10
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
19
0
0
10
19
0
10
0
19
0
10
10
% P
% Gln:
10
0
0
19
0
0
0
0
0
0
0
0
28
0
10
% Q
% Arg:
10
64
10
0
0
0
19
0
10
0
46
28
46
10
28
% R
% Ser:
0
10
0
0
19
46
10
46
0
19
0
0
0
0
10
% S
% Thr:
10
0
0
0
0
0
0
0
10
0
10
0
0
10
10
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _