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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLF1
All Species:
10
Human Site:
T216
Identified Species:
22
UniProt:
P58340
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58340
NP_001123629.1
268
30627
T216
G
R
H
N
L
G
N
T
R
M
R
S
V
G
H
Chimpanzee
Pan troglodytes
XP_516842
268
30670
T216
G
R
H
N
L
E
N
T
R
M
R
G
V
G
H
Rhesus Macaque
Macaca mulatta
XP_001102054
267
30586
T215
G
R
H
N
L
E
N
T
R
M
R
S
V
G
H
Dog
Lupus familis
XP_534319
303
34306
P251
Q
W
R
N
V
E
N
P
R
M
R
S
V
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9QWV4
267
30413
G216
I
G
R
S
G
N
T
G
M
R
S
V
G
H
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508090
246
27769
H195
N
N
L
V
T
P
K
H
K
S
V
H
H
G
S
Chicken
Gallus gallus
XP_422822
275
31455
D223
S
R
S
R
C
S
L
D
S
P
K
Y
S
S
I
Frog
Xenopus laevis
NP_001088844
245
27988
A194
E
F
L
N
L
D
E
A
E
G
P
S
F
D
D
Zebra Danio
Brachydanio rerio
NP_001020687
250
28397
P199
E
V
G
R
Y
R
P
P
T
A
R
S
L
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NKV0
376
41359
G213
Q
S
R
H
H
A
G
G
M
Q
A
I
M
P
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796343
284
31913
S216
G
G
R
S
V
E
E
S
R
P
P
V
L
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
67
N.A.
79.8
N.A.
N.A.
60.4
55.2
49.6
38
N.A.
25.7
N.A.
N.A.
35.5
Protein Similarity:
100
99.2
96.6
76.2
N.A.
90.3
N.A.
N.A.
73.8
71.6
66
53.3
N.A.
38
N.A.
N.A.
54.2
P-Site Identity:
100
86.6
93.3
60
N.A.
0
N.A.
N.A.
6.6
6.6
20
13.3
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
86.6
93.3
66.6
N.A.
6.6
N.A.
N.A.
13.3
13.3
20
26.6
N.A.
13.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
10
10
0
0
10
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
10
0
0
0
0
0
19
10
% D
% Glu:
19
0
0
0
0
37
19
0
10
0
0
0
0
0
10
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
37
19
10
0
10
10
10
19
0
10
0
10
10
46
0
% G
% His:
0
0
28
10
10
0
0
10
0
0
0
10
10
10
37
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
0
0
0
0
0
0
10
0
10
0
10
0
0
0
0
% K
% Leu:
0
0
19
0
37
0
10
0
0
0
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
19
37
0
0
10
0
0
% M
% Asn:
10
10
0
46
0
10
37
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
19
0
19
19
0
0
10
0
% P
% Gln:
19
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
37
37
19
0
10
0
0
46
10
46
0
0
0
0
% R
% Ser:
10
10
10
19
0
10
0
10
10
10
10
46
10
10
10
% S
% Thr:
0
0
0
0
10
0
10
28
10
0
0
0
0
0
0
% T
% Val:
0
10
0
10
19
0
0
0
0
0
10
19
37
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _