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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLF1
All Species:
12.73
Human Site:
T74
Identified Species:
28
UniProt:
P58340
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58340
NP_001123629.1
268
30627
T74
T
D
V
S
S
F
Q
T
M
D
Q
M
V
S
N
Chimpanzee
Pan troglodytes
XP_516842
268
30670
T74
T
D
V
S
S
F
Q
T
M
D
Q
M
V
S
N
Rhesus Macaque
Macaca mulatta
XP_001102054
267
30586
T73
T
D
V
S
P
F
Q
T
V
D
Q
M
V
S
N
Dog
Lupus familis
XP_534319
303
34306
A107
T
D
V
S
P
F
Q
A
M
D
R
M
M
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9QWV4
267
30413
T74
A
D
V
N
P
F
Q
T
M
D
R
M
M
A
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508090
246
27769
N59
R
M
M
S
N
M
R
N
S
M
Q
E
L
Q
R
Chicken
Gallus gallus
XP_422822
275
31455
A81
D
F
G
D
P
F
F
A
M
D
R
M
M
S
N
Frog
Xenopus laevis
NP_001088844
245
27988
G58
R
G
R
R
G
Q
P
G
S
Q
V
A
L
R
E
Zebra Danio
Brachydanio rerio
NP_001020687
250
28397
M63
A
L
T
P
F
G
M
M
G
M
G
G
G
F
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9NKV0
376
41359
A71
M
E
R
P
Q
M
P
A
M
P
A
M
G
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796343
284
31913
G74
A
P
F
G
M
M
G
G
M
G
S
M
F
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
93.6
67
N.A.
79.8
N.A.
N.A.
60.4
55.2
49.6
38
N.A.
25.7
N.A.
N.A.
35.5
Protein Similarity:
100
99.2
96.6
76.2
N.A.
90.3
N.A.
N.A.
73.8
71.6
66
53.3
N.A.
38
N.A.
N.A.
54.2
P-Site Identity:
100
100
86.6
66.6
N.A.
60
N.A.
N.A.
13.3
40
0
0
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
80
N.A.
86.6
N.A.
N.A.
40
53.3
6.6
0
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
0
0
0
0
0
0
28
0
0
10
10
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
46
0
10
0
0
0
0
0
55
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% E
% Phe:
0
10
10
0
10
55
10
0
0
0
0
0
10
10
10
% F
% Gly:
0
10
10
10
10
10
10
19
10
10
10
10
19
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
0
19
10
0
% L
% Met:
10
10
10
0
10
28
10
10
64
19
0
73
28
0
10
% M
% Asn:
0
0
0
10
10
0
0
10
0
0
0
0
0
0
64
% N
% Pro:
0
10
0
19
37
0
19
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
10
46
0
0
10
37
0
0
10
0
% Q
% Arg:
19
0
19
10
0
0
10
0
0
0
28
0
0
10
10
% R
% Ser:
0
0
0
46
19
0
0
0
19
0
10
0
0
37
0
% S
% Thr:
37
0
10
0
0
0
0
37
0
0
0
0
0
0
0
% T
% Val:
0
0
46
0
0
0
0
0
10
0
10
0
28
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _