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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTPN
All Species:
21.82
Human Site:
T31
Identified Species:
53.33
UniProt:
P58546
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58546
NP_665807.1
118
12895
T31
K
G
E
D
V
N
R
T
L
E
G
G
R
K
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_032124
118
12842
T31
K
G
E
D
V
N
R
T
L
E
G
G
R
K
P
Rat
Rattus norvegicus
P62775
118
12842
T31
K
G
E
D
V
N
R
T
L
E
G
G
R
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91955
118
12867
T31
K
G
E
D
V
N
R
T
L
E
G
G
R
K
P
Frog
Xenopus laevis
Q7T0Q1
118
12726
T31
G
G
V
D
V
N
R
T
L
E
G
G
R
K
P
Zebra Danio
Brachydanio rerio
Q7T2B9
118
12730
T31
K
A
E
D
V
N
R
T
L
E
G
G
R
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723568
121
13328
E34
N
D
A
Q
K
V
N
E
E
I
K
G
R
F
P
Honey Bee
Apis mellifera
XP_623750
118
13072
Q29
N
K
N
I
D
V
N
Q
M
I
D
G
R
T
P
Nematode Worm
Caenorhab. elegans
NP_508437
114
12530
E26
V
N
E
K
N
V
H
E
I
Y
N
G
R
T
A
Sea Urchin
Strong. purpuratus
XP_792242
118
12942
E25
E
L
Q
F
D
A
N
E
K
I
K
G
R
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
99.1
99.1
N.A.
N.A.
97.4
80.5
79.6
N.A.
49.5
52.5
41.5
41.5
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
99.1
99.1
N.A.
N.A.
98.3
86.4
88.9
N.A.
66.9
68.6
59.3
66.1
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
100
86.6
93.3
N.A.
20
20
20
13.3
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
100
86.6
93.3
N.A.
20
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
10
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
60
20
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
0
60
0
0
0
0
30
10
60
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
10
50
0
0
0
0
0
0
0
0
60
100
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
10
30
0
0
0
0
0
% I
% Lys:
50
10
0
10
10
0
0
0
10
0
20
0
0
60
0
% K
% Leu:
0
10
0
0
0
0
0
0
60
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
20
10
10
0
10
60
30
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% P
% Gln:
0
0
10
10
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
60
0
0
0
0
0
100
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
60
0
0
0
0
0
30
0
% T
% Val:
10
0
10
0
60
30
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _