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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTPN
All Species:
13.64
Human Site:
Y21
Identified Species:
33.33
UniProt:
P58546
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58546
NP_665807.1
118
12895
Y21
D
L
D
E
V
K
D
Y
V
A
K
G
E
D
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_032124
118
12842
Y21
D
L
D
E
V
K
D
Y
V
A
K
G
E
D
V
Rat
Rattus norvegicus
P62775
118
12842
Y21
D
L
D
E
V
K
D
Y
V
A
K
G
E
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91955
118
12867
Y21
D
L
D
E
V
K
D
Y
V
A
K
G
E
D
V
Frog
Xenopus laevis
Q7T0Q1
118
12726
F21
D
L
D
A
V
K
E
F
V
A
G
G
V
D
V
Zebra Danio
Brachydanio rerio
Q7T2B9
118
12730
I21
D
L
D
E
V
K
N
I
L
V
K
A
E
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723568
121
13328
A24
E
F
D
A
V
Q
D
A
F
Q
N
D
A
Q
K
Honey Bee
Apis mellifera
XP_623750
118
13072
I19
D
L
E
Q
V
R
D
I
V
E
N
K
N
I
D
Nematode Worm
Caenorhab. elegans
NP_508437
114
12530
K16
N
G
E
I
D
A
V
K
Q
S
V
N
E
K
N
Sea Urchin
Strong. purpuratus
XP_792242
118
12942
K15
A
Q
N
G
D
V
S
K
L
Q
E
L
Q
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
99.1
99.1
N.A.
N.A.
97.4
80.5
79.6
N.A.
49.5
52.5
41.5
41.5
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
99.1
99.1
N.A.
N.A.
98.3
86.4
88.9
N.A.
66.9
68.6
59.3
66.1
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
100
66.6
66.6
N.A.
20
33.3
6.6
0
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
100
80
80
N.A.
33.3
53.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
20
0
10
0
10
0
50
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
70
0
70
0
20
0
60
0
0
0
0
10
0
60
20
% D
% Glu:
10
0
20
50
0
0
10
0
0
10
10
0
60
0
0
% E
% Phe:
0
10
0
0
0
0
0
10
10
0
0
0
0
10
0
% F
% Gly:
0
10
0
10
0
0
0
0
0
0
10
50
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
20
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
60
0
20
0
0
50
10
0
10
10
% K
% Leu:
0
70
0
0
0
0
0
0
20
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
10
0
0
0
20
10
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
10
0
10
0
0
10
20
0
0
10
10
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
80
10
10
0
60
10
10
0
10
0
60
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _