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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FXYD7
All Species:
9.09
Human Site:
T62
Identified Species:
25
UniProt:
P58549
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58549
NP_071289.1
80
8524
T62
D
S
R
S
E
S
P
T
C
K
S
C
K
S
E
Chimpanzee
Pan troglodytes
XP_001158882
61
6792
R44
L
L
I
L
L
S
R
R
F
R
C
G
G
N
K
Rhesus Macaque
Macaca mulatta
XP_001111156
59
6124
C42
S
R
S
E
S
P
T
C
K
S
C
K
S
E
L
Dog
Lupus familis
XP_533697
92
10512
P73
Q
Q
Q
R
T
G
E
P
D
E
E
E
G
T
F
Cat
Felis silvestris
Mouse
Mus musculus
P59648
80
8468
T62
D
S
R
S
E
S
P
T
C
K
S
C
K
S
E
Rat
Rattus norvegicus
P59649
80
8468
T62
D
S
R
S
E
S
P
T
C
K
S
C
K
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521655
64
7012
K47
L
I
I
I
L
S
K
K
F
R
C
G
G
R
K
Chicken
Gallus gallus
NP_001074348
95
10193
D74
Q
K
P
R
A
P
G
D
E
E
A
Q
G
E
N
Frog
Xenopus laevis
O13001
61
6981
G44
G
M
L
I
I
F
S
G
R
F
R
C
G
R
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.5
73.7
30.4
N.A.
86.2
87.5
N.A.
27.5
25.2
28.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
50
73.7
46.7
N.A.
95
95
N.A.
48.7
44.2
43.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
0
N.A.
100
100
N.A.
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
0
20
N.A.
100
100
N.A.
20
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
34
0
34
45
0
0
0
% C
% Asp:
34
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% D
% Glu:
0
0
0
12
34
0
12
0
12
23
12
12
0
23
34
% E
% Phe:
0
0
0
0
0
12
0
0
23
12
0
0
0
0
12
% F
% Gly:
12
0
0
0
0
12
12
12
0
0
0
23
56
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
23
23
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
12
12
12
34
0
12
34
0
34
% K
% Leu:
23
12
12
12
23
0
0
0
0
0
0
0
0
0
12
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% N
% Pro:
0
0
12
0
0
23
34
12
0
0
0
0
0
0
0
% P
% Gln:
23
12
12
0
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
0
12
34
23
0
0
12
12
12
23
12
0
0
23
0
% R
% Ser:
12
34
12
34
12
56
12
0
0
12
34
0
12
34
0
% S
% Thr:
0
0
0
0
12
0
12
34
0
0
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _