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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FXYD8
All Species:
17.27
Human Site:
T83
Identified Species:
42.22
UniProt:
P58550
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P58550
NP_071286
94
10590
T83
A
Q
V
E
N
F
I
T
A
N
A
K
E
P
Q
Chimpanzee
Pan troglodytes
XP_001141252
95
10662
I84
A
Q
V
E
N
F
I
I
A
N
A
K
A
P
Q
Rhesus Macaque
Macaca mulatta
XP_001095176
95
10702
I84
A
Q
V
E
N
F
I
I
A
N
A
K
E
P
Q
Dog
Lupus familis
XP_853482
94
10395
T83
A
Q
V
E
N
L
I
T
A
N
A
T
E
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D164
94
10356
T83
A
Q
V
E
N
L
I
T
T
N
A
A
E
P
Q
Rat
Rattus norvegicus
Q91XV6
94
10370
T83
A
Q
V
E
N
L
I
T
T
N
A
A
E
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521652
95
10484
T84
T
Q
A
E
T
L
I
T
S
N
A
T
E
P
Q
Chicken
Gallus gallus
NP_001074348
95
10193
T84
A
Q
G
E
N
L
I
T
S
N
A
T
G
A
Q
Frog
Xenopus laevis
O13001
61
6981
L54
R
C
G
R
K
K
Q
L
R
A
L
N
D
D
M
Zebra Danio
Brachydanio rerio
NP_956141
99
10728
V88
A
P
A
E
N
L
M
V
S
K
T
K
E
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
85.2
73.4
N.A.
74.4
75.5
N.A.
66.3
62.1
21.2
51.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.7
90.5
81.9
N.A.
82.9
82.9
N.A.
76.8
75.7
39.3
67.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
93.3
86.6
N.A.
80
80
N.A.
60
60
0
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
93.3
86.6
N.A.
80
80
N.A.
66.6
66.6
6.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
80
0
20
0
0
0
0
0
40
10
80
20
10
10
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% D
% Glu:
0
0
0
90
0
0
0
0
0
0
0
0
70
0
0
% E
% Phe:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
20
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
80
20
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
10
0
0
0
10
0
40
0
0
0
% K
% Leu:
0
0
0
0
0
60
0
10
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
80
0
0
0
0
80
0
10
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
0
70
10
% P
% Gln:
0
80
0
0
0
0
10
0
0
0
0
0
0
0
80
% Q
% Arg:
10
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
10
0
0
60
20
0
10
30
0
10
0
% T
% Val:
0
0
60
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _