Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C21orf57 All Species: 4.24
Human Site: S21 Identified Species: 11.67
UniProt: P58557 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P58557 NP_478061.1 167 19298 S21 I R R A P L R S K I E I V R R
Chimpanzee Pan troglodytes XP_001145583 251 28308 P41 G P R C P L A P R K D L R R K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848242 164 18795 S21 V R R A P L R S R V E L L R A
Cat Felis silvestris
Mouse Mus musculus Q8CAV0 164 18970 R21 I R R V P L R R K M D L V R S
Rat Rattus norvegicus NP_001101999 164 19053 R21 I R R M P L R R K M D L V R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514071 165 19358 Q21 I R R V P L R Q K I E T L R R
Chicken Gallus gallus
Frog Xenopus laevis NP_001087112 165 18992 F21 L Y R A H L R F S L D I A R S
Zebra Danio Brachydanio rerio NP_997759 163 19317 R21 V R R A R L R R D V E I L R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793533 182 20962 G21 F N L D K V K G D L K A L R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48.6 N.A. 66.4 N.A. 76 78.4 N.A. 74.2 N.A. 53.8 57.4 N.A. N.A. N.A. N.A. 42.3
Protein Similarity: 100 55.3 N.A. 82.6 N.A. 88 89.2 N.A. 85 N.A. 70.6 71.2 N.A. N.A. N.A. N.A. 62.6
P-Site Identity: 100 26.6 N.A. 60 N.A. 60 60 N.A. 73.3 N.A. 40 53.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 53.3 N.A. 93.3 N.A. 80 80 N.A. 80 N.A. 60 73.3 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 45 0 0 12 0 0 0 0 12 12 0 12 % A
% Cys: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 12 0 0 0 0 23 0 45 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 45 0 0 0 0 % E
% Phe: 12 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 12 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 12 % H
% Ile: 45 0 0 0 0 0 0 0 0 23 0 34 0 0 0 % I
% Lys: 0 0 0 0 12 0 12 0 45 12 12 0 0 0 12 % K
% Leu: 12 0 12 0 0 89 0 0 0 23 0 45 45 0 0 % L
% Met: 0 0 0 12 0 0 0 0 0 23 0 0 0 0 0 % M
% Asn: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 0 0 67 0 0 12 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % Q
% Arg: 0 67 89 0 12 0 78 34 23 0 0 0 12 100 34 % R
% Ser: 0 0 0 0 0 0 0 23 12 0 0 0 0 0 34 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % T
% Val: 23 0 0 23 0 12 0 0 0 23 0 0 34 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _