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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C21orf57 All Species: 29.09
Human Site: S65 Identified Species: 80
UniProt: P58557 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P58557 NP_478061.1 167 19298 S65 N V P T D V L S F P F H E H L
Chimpanzee Pan troglodytes XP_001145583 251 28308 R145 Q R V I P I R R A P L R S K I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848242 164 18795 S65 D R P T D V L S F P F H E N V
Cat Felis silvestris
Mouse Mus musculus Q8CAV0 164 18970 S65 N V P T D V L S F S F H E N L
Rat Rattus norvegicus NP_001101999 164 19053 S65 N V P T D V L S F P F H E N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514071 165 19358 S65 N V P T D V L S F P F H E N L
Chicken Gallus gallus
Frog Xenopus laevis NP_001087112 165 18992 S65 D S V T D V L S F P F H E D L
Zebra Danio Brachydanio rerio NP_997759 163 19317 S65 N Q P T D V L S F P F Y E D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793533 182 20962 S65 D E P T D V L S F P A H E N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48.6 N.A. 66.4 N.A. 76 78.4 N.A. 74.2 N.A. 53.8 57.4 N.A. N.A. N.A. N.A. 42.3
Protein Similarity: 100 55.3 N.A. 82.6 N.A. 88 89.2 N.A. 85 N.A. 70.6 71.2 N.A. N.A. N.A. N.A. 62.6
P-Site Identity: 100 6.6 N.A. 73.3 N.A. 86.6 93.3 N.A. 93.3 N.A. 73.3 80 N.A. N.A. N.A. N.A. 73.3
P-Site Similarity: 100 20 N.A. 93.3 N.A. 93.3 100 N.A. 100 N.A. 80 86.6 N.A. N.A. N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 12 0 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 34 0 0 0 89 0 0 0 0 0 0 0 0 23 0 % D
% Glu: 0 12 0 0 0 0 0 0 0 0 0 0 89 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 89 0 78 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 78 0 12 0 % H
% Ile: 0 0 0 12 0 12 0 0 0 0 0 0 0 0 12 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % K
% Leu: 0 0 0 0 0 0 89 0 0 0 12 0 0 0 78 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 56 0 0 0 0 0 0 0 0 0 0 0 0 56 0 % N
% Pro: 0 0 78 0 12 0 0 0 0 89 0 0 0 0 0 % P
% Gln: 12 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 23 0 0 0 0 12 12 0 0 0 12 0 0 0 % R
% Ser: 0 12 0 0 0 0 0 89 0 12 0 0 12 0 0 % S
% Thr: 0 0 0 89 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 45 23 0 0 89 0 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _