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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C21orf57 All Species: 7.58
Human Site: T152 Identified Species: 20.83
UniProt: P58557 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P58557 NP_478061.1 167 19298 T152 L D E L G R R T G T R L Q P L
Chimpanzee Pan troglodytes XP_001145583 251 28308 T236 L D E L G R R T G T R L Q P L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848242 164 18795 L148 E K Q V L E E L S R L T G T R
Cat Felis silvestris
Mouse Mus musculus Q8CAV0 164 18970 E147 Q E K L V L E E L S R Y T G A
Rat Rattus norvegicus NP_001101999 164 19053 E147 Q E K L V L E E L S R H T G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514071 165 19358 I145 M Y Q K E K H I L D E L N K L
Chicken Gallus gallus
Frog Xenopus laevis NP_001087112 165 18992 I145 M F E K E T E I L N E I N R V
Zebra Danio Brachydanio rerio NP_997759 163 19317 E148 K E S Y I L S E F N R L T G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793533 182 20962 T152 L E Q F K K L T G Q D L Q P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48.6 N.A. 66.4 N.A. 76 78.4 N.A. 74.2 N.A. 53.8 57.4 N.A. N.A. N.A. N.A. 42.3
Protein Similarity: 100 55.3 N.A. 82.6 N.A. 88 89.2 N.A. 85 N.A. 70.6 71.2 N.A. N.A. N.A. N.A. 62.6
P-Site Identity: 100 100 N.A. 0 N.A. 13.3 13.3 N.A. 13.3 N.A. 6.6 13.3 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 100 N.A. 13.3 N.A. 33.3 33.3 N.A. 33.3 N.A. 26.6 20 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 23 0 0 0 0 0 0 0 12 12 0 0 0 0 % D
% Glu: 12 45 34 0 23 12 45 34 0 0 23 0 0 0 0 % E
% Phe: 0 12 0 12 0 0 0 0 12 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 23 0 0 0 34 0 0 0 12 34 0 % G
% His: 0 0 0 0 0 0 12 0 0 0 0 12 0 0 0 % H
% Ile: 0 0 0 0 12 0 0 23 0 0 0 12 0 0 0 % I
% Lys: 12 12 23 23 12 23 0 0 0 0 0 0 0 12 0 % K
% Leu: 34 0 0 45 12 34 12 12 45 0 12 56 0 0 45 % L
% Met: 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 23 0 0 23 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 34 0 % P
% Gln: 23 0 34 0 0 0 0 0 0 12 0 0 34 0 0 % Q
% Arg: 0 0 0 0 0 23 23 0 0 12 56 0 0 12 12 % R
% Ser: 0 0 12 0 0 0 12 0 12 23 0 0 0 0 12 % S
% Thr: 0 0 0 0 0 12 0 34 0 23 0 12 34 12 0 % T
% Val: 0 0 0 12 23 0 0 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 12 0 0 0 0 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _