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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C21orf63 All Species: 22.42
Human Site: Y401 Identified Species: 61.67
UniProt: P58658 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P58658 NP_478067.2 441 49483 Y401 C R T S Y P I Y S S I E A A E
Chimpanzee Pan troglodytes Q68US5 441 49367 Y401 C R T S Y P V Y S S I E A A E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535579 441 49266 Y401 C R T S Y P V Y S S I E A A E
Cat Felis silvestris
Mouse Mus musculus P58659 440 49269 Y400 C R T S Y P A Y S S I E A A E
Rat Rattus norvegicus XP_340967 440 49157 Y400 C R T T Y P A Y S S I E A A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519987 390 42260 E360 P E A A D L A E R L E W R D Q
Chicken Gallus gallus XP_416704 435 48629 Y391 Y R P S Y S G Y N S A E A A D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_692814 438 49580 T389 V Y C W E D V T Y T T E A A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_493590 461 52054 R410 S S R R S R S R R S L E T S K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 N.A. 91.3 N.A. 86.1 85.4 N.A. 56.9 65.5 N.A. 42.8 N.A. N.A. N.A. 24.5 N.A.
Protein Similarity: 100 99.3 N.A. 94 N.A. 92.5 91.8 N.A. 69.1 77.5 N.A. 60.3 N.A. N.A. N.A. 44 N.A.
P-Site Identity: 100 93.3 N.A. 93.3 N.A. 93.3 86.6 N.A. 0 53.3 N.A. 20 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 13.3 66.6 N.A. 40 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 12 0 0 34 0 0 0 12 0 78 78 0 % A
% Cys: 56 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 12 12 0 0 0 0 0 0 0 12 23 % D
% Glu: 0 12 0 0 12 0 0 12 0 0 12 89 0 0 56 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 0 0 56 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % K
% Leu: 0 0 0 0 0 12 0 0 0 12 12 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % N
% Pro: 12 0 12 0 0 56 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % Q
% Arg: 0 67 12 12 0 12 0 12 23 0 0 0 12 0 0 % R
% Ser: 12 12 0 56 12 12 12 0 56 78 0 0 0 12 0 % S
% Thr: 0 0 56 12 0 0 0 12 0 12 12 0 12 0 0 % T
% Val: 12 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 12 0 0 0 0 0 0 0 12 0 0 0 % W
% Tyr: 12 12 0 0 67 0 0 67 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _