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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC26A5 All Species: 14.55
Human Site: T624 Identified Species: 29.09
UniProt: P58743 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P58743 NP_945350.1 744 81264 T624 P P I V I K S T F P E E M Q R
Chimpanzee Pan troglodytes XP_001145955 504 54853 F388 C N S I G S L F Q T F S I S C
Rhesus Macaque Macaca mulatta XP_001084716 505 55044 T390 S I G S L F Q T F S I S C S L
Dog Lupus familis XP_540393 744 81203 T624 P P I V I K S T F P E E L Q R
Cat Felis silvestris
Mouse Mus musculus Q99NH7 744 81302 T624 P P I V I K T T F P E E L Q R
Rat Rattus norvegicus Q9EPH0 744 81260 T624 P P I V I K T T F P E E L Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507963 744 81520 I623 G K G P A E P I V Q N T F P E
Chicken Gallus gallus NP_001072945 742 81094 G627 N D G L P A N G K F A F V D A
Frog Xenopus laevis NP_001086349 726 79928 Q595 K N I L S K T Q M G T G L E F
Zebra Danio Brachydanio rerio NP_958881 739 81386 H624 N G P Q K P K H V H T N G Q M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94225 782 87457 L648 D Y L G L S T L K S V Y V D L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FY46 685 75077 I569 R G L E V D R I N F V I L E M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.6 67.6 96.7 N.A. 94.8 94.4 N.A. 77.6 58.7 43.1 52.8 N.A. N.A. N.A. 26.4 N.A.
Protein Similarity: 100 67.7 67.7 98.3 N.A. 97.5 97.4 N.A. 87.5 75.8 60.6 69.8 N.A. N.A. N.A. 47.5 N.A.
P-Site Identity: 100 0 13.3 93.3 N.A. 86.6 86.6 N.A. 0 0 13.3 6.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 13.3 20 100 N.A. 100 100 N.A. 6.6 20 40 6.6 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 9 0 0 0 0 9 0 0 0 9 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % C
% Asp: 9 9 0 0 0 9 0 0 0 0 0 0 0 17 0 % D
% Glu: 0 0 0 9 0 9 0 0 0 0 34 34 0 17 9 % E
% Phe: 0 0 0 0 0 9 0 9 42 17 9 9 9 0 9 % F
% Gly: 9 17 25 9 9 0 0 9 0 9 0 9 9 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % H
% Ile: 0 9 42 9 34 0 0 17 0 0 9 9 9 0 0 % I
% Lys: 9 9 0 0 9 42 9 0 17 0 0 0 0 0 0 % K
% Leu: 0 0 17 17 17 0 9 9 0 0 0 0 42 0 17 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 17 % M
% Asn: 17 17 0 0 0 0 9 0 9 0 9 9 0 0 0 % N
% Pro: 34 34 9 9 9 9 9 0 0 34 0 0 0 9 0 % P
% Gln: 0 0 0 9 0 0 9 9 9 9 0 0 0 42 0 % Q
% Arg: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 34 % R
% Ser: 9 0 9 9 9 17 17 0 0 17 0 17 0 17 0 % S
% Thr: 0 0 0 0 0 0 34 42 0 9 17 9 0 0 0 % T
% Val: 0 0 0 34 9 0 0 0 17 0 17 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _