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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NLRP6
All Species:
9.09
Human Site:
S473
Identified Species:
28.57
UniProt:
P59044
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59044
NP_612202.1
892
98768
S473
E
Q
L
E
L
R
G
S
K
V
Q
T
L
F
L
Chimpanzee
Pan troglodytes
Q8HZP9
461
49911
C75
L
G
D
V
G
V
H
C
V
L
Q
G
L
Q
S
Rhesus Macaque
Macaca mulatta
B0FPE9
1035
118173
K496
L
R
N
H
G
L
Q
K
A
D
V
S
A
F
L
Dog
Lupus familis
XP_540513
907
101142
L467
M
R
A
E
L
R
K
L
C
R
L
A
R
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91WS2
869
97383
S471
E
K
L
K
L
R
G
S
Q
V
Q
T
I
F
L
Rat
Rattus norvegicus
Q63035
880
98190
S470
E
R
L
K
L
Q
G
S
Q
V
Q
T
M
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519466
420
46978
F34
K
Q
D
E
F
K
K
F
G
H
K
L
V
T
I
Chicken
Gallus gallus
XP_001233262
925
103041
P443
E
D
Q
G
L
N
Q
P
Q
L
L
S
L
F
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.4
28.7
70.4
N.A.
70
72
N.A.
26.6
30.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
31.3
44.8
78
N.A.
80
80.9
N.A.
34.4
46.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
20
N.A.
73.3
66.6
N.A.
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
26.6
26.6
N.A.
100
100
N.A.
46.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
0
0
0
13
0
0
13
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
13
13
0
0
0
0
0
0
% C
% Asp:
0
13
25
0
0
0
0
0
0
13
0
0
0
0
0
% D
% Glu:
50
0
0
38
0
0
0
0
0
0
0
0
0
13
0
% E
% Phe:
0
0
0
0
13
0
0
13
0
0
0
0
0
63
0
% F
% Gly:
0
13
0
13
25
0
38
0
13
0
0
13
0
0
13
% G
% His:
0
0
0
13
0
0
13
0
0
13
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
13
% I
% Lys:
13
13
0
25
0
13
25
13
13
0
13
0
0
0
0
% K
% Leu:
25
0
38
0
63
13
0
13
0
25
25
13
38
0
63
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
0
13
0
0
13
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% P
% Gln:
0
25
13
0
0
13
25
0
38
0
50
0
0
13
0
% Q
% Arg:
0
38
0
0
0
38
0
0
0
13
0
0
13
0
0
% R
% Ser:
0
0
0
0
0
0
0
38
0
0
0
25
0
0
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
38
0
13
0
% T
% Val:
0
0
0
13
0
13
0
0
13
38
13
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _