KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NLRP5
All Species:
0.91
Human Site:
T256
Identified Species:
5
UniProt:
P59047
Number Species:
4
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59047
NP_703148.4
1200
134342
T256
V
R
R
S
F
E
N
T
A
A
D
W
P
E
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
B0FPE9
1035
118173
R172
N
K
R
Y
T
R
L
R
L
I
K
E
H
R
S
Dog
Lupus familis
XP_533576
1100
124911
R237
S
F
A
E
L
I
S
R
E
W
P
D
Y
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1M5
1163
131299
T244
Q
K
T
F
Q
P
H
T
I
I
L
H
G
R
P
Rat
Rattus norvegicus
Q63035
880
98190
E17
S
S
E
A
V
A
R
E
L
L
L
A
A
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
28.1
59.9
N.A.
48
24.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
46.6
71.2
N.A.
65.7
38
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
0
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
20
N.A.
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
20
0
20
0
0
20
20
0
20
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
20
20
0
0
0
% D
% Glu:
0
0
20
20
0
20
0
20
20
0
0
20
0
20
0
% E
% Phe:
0
20
0
20
20
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% G
% His:
0
0
0
0
0
0
20
0
0
0
0
20
20
0
0
% H
% Ile:
0
0
0
0
0
20
0
0
20
40
0
0
0
0
0
% I
% Lys:
0
40
0
0
0
0
0
0
0
0
20
0
0
0
0
% K
% Leu:
0
0
0
0
20
0
20
0
40
20
40
0
0
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% M
% Asn:
20
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
20
0
0
0
0
20
0
20
0
20
% P
% Gln:
20
0
0
0
20
0
0
0
0
0
0
0
0
20
20
% Q
% Arg:
0
20
40
0
0
20
20
40
0
0
0
0
0
40
0
% R
% Ser:
40
20
0
20
0
0
20
0
0
0
0
0
0
0
20
% S
% Thr:
0
0
20
0
20
0
0
40
0
0
0
0
0
0
0
% T
% Val:
20
0
0
0
20
0
0
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
20
0
20
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
0
0
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _