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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPPP2
All Species:
11.82
Human Site:
T23
Identified Species:
21.67
UniProt:
P59282
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59282
NP_776245.2
170
18503
T23
G
E
S
S
S
S
G
T
E
M
N
N
K
N
F
Chimpanzee
Pan troglodytes
XP_517605
219
23707
K69
G
D
T
R
A
T
G
K
E
M
H
G
K
N
W
Rhesus Macaque
Macaca mulatta
XP_001093843
170
18401
T23
G
E
S
S
S
S
G
T
E
M
N
N
K
N
F
Dog
Lupus familis
XP_532620
171
18599
T23
G
E
S
S
S
S
G
T
E
M
N
N
K
N
F
Cat
Felis silvestris
Mouse
Mus musculus
Q0P5Y3
170
18662
K23
G
E
S
S
S
S
S
K
E
I
T
N
K
N
F
Rat
Rattus norvegicus
Q5PPN5
176
18961
Q28
G
D
P
K
A
S
G
Q
E
M
N
G
K
N
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505656
252
27673
R102
G
D
T
R
A
T
G
R
E
M
H
G
K
N
W
Chicken
Gallus gallus
XP_424853
201
21484
N55
G
D
T
A
A
S
G
N
N
M
T
G
K
N
F
Frog
Xenopus laevis
Q2VPM9
176
19075
Q28
G
D
T
K
A
T
G
Q
E
M
T
G
K
N
W
Zebra Danio
Brachydanio rerio
XP_687926
181
19631
K31
G
D
T
K
A
T
G
K
E
M
N
G
K
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VV43
192
20578
F37
E
D
E
P
K
V
S
F
S
D
Q
F
K
A
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91127
180
19387
T30
K
F
G
A
A
T
A
T
E
M
T
G
K
N
F
Sea Urchin
Strong. purpuratus
XP_782492
171
18740
A24
G
A
G
S
K
D
A
A
P
V
M
D
N
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.1
97
88.3
N.A.
84.1
62.5
N.A.
40
55.2
59.6
59.1
N.A.
34.9
N.A.
40.5
50.2
Protein Similarity:
100
61.6
98.8
92.4
N.A.
91.1
78.4
N.A.
53.1
70.6
76.1
72.3
N.A.
44.7
N.A.
55.5
66
P-Site Identity:
100
40
100
100
N.A.
73.3
53.3
N.A.
40
46.6
40
53.3
N.A.
13.3
N.A.
40
13.3
P-Site Similarity:
100
80
100
100
N.A.
80
73.3
N.A.
80
73.3
73.3
80
N.A.
20
N.A.
60
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
54
0
16
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
54
0
0
0
8
0
0
0
8
0
8
0
0
0
% D
% Glu:
8
31
8
0
0
0
0
0
77
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
8
0
0
62
% F
% Gly:
85
0
16
0
0
0
70
0
0
0
0
54
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
0
24
16
0
0
24
0
0
0
0
93
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
77
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
39
31
8
85
0
% N
% Pro:
0
0
8
8
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
16
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
16
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
31
39
31
47
16
0
8
0
0
0
0
8
0
% S
% Thr:
0
0
39
0
0
39
0
31
0
0
31
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _