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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPPP2
All Species:
24.24
Human Site:
T66
Identified Species:
44.44
UniProt:
P59282
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59282
NP_776245.2
170
18503
T66
A
K
N
A
R
T
I
T
F
Q
Q
F
K
E
A
Chimpanzee
Pan troglodytes
XP_517605
219
23707
T112
G
K
S
C
R
T
I
T
F
E
Q
F
Q
E
A
Rhesus Macaque
Macaca mulatta
XP_001093843
170
18401
T66
A
K
N
A
R
T
I
T
F
Q
Q
F
K
E
A
Dog
Lupus familis
XP_532620
171
18599
T66
A
K
N
A
R
T
I
T
F
Q
Q
F
Q
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q0P5Y3
170
18662
N66
A
K
N
A
R
T
I
N
F
Q
Q
F
Q
E
A
Rat
Rattus norvegicus
Q5PPN5
176
18961
N71
A
K
S
A
R
V
I
N
Y
E
E
F
K
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505656
252
27673
T145
G
K
S
C
R
T
I
T
F
D
Q
F
K
E
A
Chicken
Gallus gallus
XP_424853
201
21484
N98
T
K
G
A
R
T
I
N
F
V
E
F
Q
Q
A
Frog
Xenopus laevis
Q2VPM9
176
19075
T71
A
K
S
A
R
V
I
T
Y
E
E
F
T
K
A
Zebra Danio
Brachydanio rerio
XP_687926
181
19631
T74
V
K
S
A
R
V
I
T
F
E
Q
F
T
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VV43
192
20578
D80
D
K
K
I
T
T
T
D
T
G
I
H
F
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91127
180
19387
F73
G
P
K
K
K
A
T
F
D
E
T
K
K
V
L
Sea Urchin
Strong. purpuratus
XP_782492
171
18740
K67
V
K
S
K
T
D
R
K
I
N
F
A
Q
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.1
97
88.3
N.A.
84.1
62.5
N.A.
40
55.2
59.6
59.1
N.A.
34.9
N.A.
40.5
50.2
Protein Similarity:
100
61.6
98.8
92.4
N.A.
91.1
78.4
N.A.
53.1
70.6
76.1
72.3
N.A.
44.7
N.A.
55.5
66
P-Site Identity:
100
66.6
100
93.3
N.A.
86.6
53.3
N.A.
73.3
53.3
53.3
60
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
86.6
100
100
N.A.
93.3
86.6
N.A.
80
73.3
86.6
80
N.A.
20
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
0
62
0
8
0
0
0
0
0
8
0
0
77
% A
% Cys:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
8
8
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
39
24
0
0
47
0
% E
% Phe:
0
0
0
0
0
0
0
8
62
0
8
77
8
8
0
% F
% Gly:
24
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
8
0
0
77
0
8
0
8
0
0
0
0
% I
% Lys:
0
93
16
16
8
0
0
8
0
0
0
8
39
24
16
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
31
0
0
0
0
24
0
8
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
31
54
0
39
16
0
% Q
% Arg:
0
0
0
0
77
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
47
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
16
62
16
54
8
0
8
0
16
0
0
% T
% Val:
16
0
0
0
0
24
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _