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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPPP2
All Species:
39.7
Human Site:
Y155
Identified Species:
72.78
UniProt:
P59282
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59282
NP_776245.2
170
18503
Y155
E
M
T
D
N
T
G
Y
V
S
G
Y
K
G
S
Chimpanzee
Pan troglodytes
XP_517605
219
23707
Y201
D
L
V
D
E
S
G
Y
V
S
G
Y
K
H
A
Rhesus Macaque
Macaca mulatta
XP_001093843
170
18401
Y155
V
M
N
D
N
T
G
Y
V
S
G
Y
K
G
A
Dog
Lupus familis
XP_532620
171
18599
Y155
E
A
T
D
N
S
G
Y
V
S
G
Y
K
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q0P5Y3
170
18662
Y155
E
T
T
D
N
S
G
Y
V
S
G
Y
K
G
A
Rat
Rattus norvegicus
Q5PPN5
176
18961
Y160
D
I
L
D
D
S
G
Y
V
S
A
Y
K
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505656
252
27673
Y234
D
L
V
D
D
S
G
Y
V
P
G
Y
K
H
A
Chicken
Gallus gallus
XP_424853
201
21484
Y187
D
L
T
D
N
S
G
Y
V
G
A
Y
K
G
A
Frog
Xenopus laevis
Q2VPM9
176
19075
Y160
T
I
V
E
N
T
G
Y
V
G
S
Y
K
L
A
Zebra Danio
Brachydanio rerio
XP_687926
181
19631
Y163
D
I
P
D
T
S
G
Y
V
S
A
Y
K
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VV43
192
20578
Y178
N
V
V
D
G
S
G
Y
V
S
G
Y
Q
H
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91127
180
19387
Y164
D
T
T
E
N
T
G
Y
V
G
A
Y
K
N
K
Sea Urchin
Strong. purpuratus
XP_782492
171
18740
E156
D
F
D
A
K
A
A
E
G
Y
V
G
G
Y
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.1
97
88.3
N.A.
84.1
62.5
N.A.
40
55.2
59.6
59.1
N.A.
34.9
N.A.
40.5
50.2
Protein Similarity:
100
61.6
98.8
92.4
N.A.
91.1
78.4
N.A.
53.1
70.6
76.1
72.3
N.A.
44.7
N.A.
55.5
66
P-Site Identity:
100
53.3
80
80
N.A.
80
46.6
N.A.
46.6
60
46.6
53.3
N.A.
46.6
N.A.
53.3
0
P-Site Similarity:
100
80
86.6
93.3
N.A.
93.3
80
N.A.
80
86.6
66.6
73.3
N.A.
66.6
N.A.
66.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
8
8
0
0
0
31
0
0
0
62
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
8
77
16
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
24
0
0
16
8
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
93
0
8
24
54
8
8
47
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
0
% H
% Ile:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
85
0
24
% K
% Leu:
0
24
8
0
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
54
0
0
0
0
0
0
0
0
16
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
62
0
0
0
62
8
0
0
0
8
% S
% Thr:
8
16
39
0
8
31
0
0
0
0
0
0
0
0
0
% T
% Val:
8
8
31
0
0
0
0
0
93
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
8
0
93
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _