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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS20
All Species:
7.58
Human Site:
S249
Identified Species:
15.15
UniProt:
P59510
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59510
NP_079279.3
1910
214721
S249
L
K
D
E
R
R
H
S
R
K
K
R
L
I
S
Chimpanzee
Pan troglodytes
XP_528704
1935
216502
R283
T
R
E
K
R
T
H
R
R
T
K
R
F
L
S
Rhesus Macaque
Macaca mulatta
NP_001104009
1911
214939
S250
D
E
R
S
Q
L
H
S
R
K
K
R
L
I
S
Dog
Lupus familis
XP_852138
2091
233309
S252
D
E
R
S
Q
L
H
S
R
K
K
R
F
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P59511
1906
212023
K248
S
Q
L
H
S
R
N
K
R
F
L
S
Y
P
R
Rat
Rattus norvegicus
Q9WUQ1
967
105687
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505519
1995
223408
T252
N
F
C
L
W
Q
Q
T
Q
N
T
L
D
D
S
Chicken
Gallus gallus
XP_416037
1725
194026
D120
V
E
V
M
V
T
A
D
T
K
M
V
R
H
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663807
2516
282446
F248
R
F
L
S
Y
P
R
F
V
E
V
M
V
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395557
1763
199932
L158
R
E
N
P
G
P
E
L
G
C
F
Y
S
G
T
Nematode Worm
Caenorhab. elegans
Q19791
2150
242563
R270
D
V
I
E
R
K
A
R
S
R
R
A
A
N
S
Sea Urchin
Strong. purpuratus
XP_791211
1693
190452
I87
V
Y
S
L
I
E
S
I
Q
N
S
L
Q
W
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.3
94.1
69.1
N.A.
70.3
23.5
N.A.
57.2
57.1
N.A.
32.6
N.A.
N.A.
32
31.5
38.1
Protein Similarity:
100
67.6
96.9
78.3
N.A.
83.4
31.2
N.A.
70.7
71.7
N.A.
46.6
N.A.
N.A.
46.9
47
53.5
P-Site Identity:
100
40
60
46.6
N.A.
13.3
0
N.A.
6.6
6.6
N.A.
0
N.A.
N.A.
0
20
0
P-Site Similarity:
100
66.6
73.3
66.6
N.A.
26.6
0
N.A.
26.6
20
N.A.
26.6
N.A.
N.A.
20
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
17
0
0
0
0
9
9
0
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
25
0
9
0
0
0
0
9
0
0
0
0
9
9
0
% D
% Glu:
0
34
9
17
0
9
9
0
0
9
0
0
0
0
0
% E
% Phe:
0
17
0
0
0
0
0
9
0
9
9
0
17
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
9
0
0
0
0
9
0
% G
% His:
0
0
0
9
0
0
34
0
0
0
0
0
0
9
9
% H
% Ile:
0
0
9
0
9
0
0
9
0
0
0
0
0
17
0
% I
% Lys:
0
9
0
9
0
9
0
9
0
34
34
0
0
0
9
% K
% Leu:
9
0
17
17
0
17
0
9
0
0
9
17
17
17
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
9
0
9
0
0
0
9
0
0
17
0
0
0
9
0
% N
% Pro:
0
0
0
9
0
17
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
9
0
0
17
9
9
0
17
0
0
0
9
0
0
% Q
% Arg:
17
9
17
0
25
17
9
17
42
9
9
34
9
0
9
% R
% Ser:
9
0
9
25
9
0
9
25
9
0
9
9
9
0
50
% S
% Thr:
9
0
0
0
0
17
0
9
9
9
9
0
0
0
9
% T
% Val:
17
9
9
0
9
0
0
0
9
0
9
9
9
9
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
9
0
0
9
0
0
0
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _