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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS20
All Species:
18.48
Human Site:
Y924
Identified Species:
36.97
UniProt:
P59510
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59510
NP_079279.3
1910
214721
Y924
S
S
Q
C
G
Q
G
Y
R
T
L
D
I
H
C
Chimpanzee
Pan troglodytes
XP_528704
1935
216502
Y955
S
A
Q
C
G
L
G
Y
R
T
L
D
I
Y
C
Rhesus Macaque
Macaca mulatta
NP_001104009
1911
214939
Y925
S
T
Q
C
G
Q
G
Y
R
T
L
D
I
H
C
Dog
Lupus familis
XP_852138
2091
233309
Y927
S
S
H
C
G
Q
G
Y
R
S
L
D
V
H
C
Cat
Felis silvestris
Mouse
Mus musculus
P59511
1906
212023
Y920
S
S
Q
C
G
Q
G
Y
R
T
L
D
V
H
C
Rat
Rattus norvegicus
Q9WUQ1
967
105687
S9
Q
P
E
V
P
L
G
S
G
K
L
K
P
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505519
1995
223408
H956
T
C
G
K
G
T
K
H
R
Q
V
W
C
R
L
Chicken
Gallus gallus
XP_416037
1725
194026
D767
W
H
S
I
G
K
S
D
C
T
S
K
C
G
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663807
2516
282446
E91
T
I
L
G
A
S
S
E
G
H
N
S
V
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395557
1763
199932
V805
Y
S
G
R
D
S
R
V
E
R
L
N
T
S
R
Nematode Worm
Caenorhab. elegans
Q19791
2150
242563
Q963
S
A
K
C
G
S
G
Q
K
R
Q
R
V
S
C
Sea Urchin
Strong. purpuratus
XP_791211
1693
190452
D734
R
R
V
I
R
C
M
D
A
N
D
N
R
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.3
94.1
69.1
N.A.
70.3
23.5
N.A.
57.2
57.1
N.A.
32.6
N.A.
N.A.
32
31.5
38.1
Protein Similarity:
100
67.6
96.9
78.3
N.A.
83.4
31.2
N.A.
70.7
71.7
N.A.
46.6
N.A.
N.A.
46.9
47
53.5
P-Site Identity:
100
80
93.3
80
N.A.
93.3
13.3
N.A.
13.3
13.3
N.A.
0
N.A.
N.A.
13.3
33.3
0
P-Site Similarity:
100
93.3
100
93.3
N.A.
100
20
N.A.
33.3
20
N.A.
13.3
N.A.
N.A.
20
60
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
9
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
9
0
50
0
9
0
0
9
0
0
0
17
9
50
% C
% Asp:
0
0
0
0
9
0
0
17
0
0
9
42
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
9
9
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
9
67
0
59
0
17
0
0
0
0
9
9
% G
% His:
0
9
9
0
0
0
0
9
0
9
0
0
0
34
0
% H
% Ile:
0
9
0
17
0
0
0
0
0
0
0
0
25
0
0
% I
% Lys:
0
0
9
9
0
9
9
0
9
9
0
17
0
0
0
% K
% Leu:
0
0
9
0
0
17
0
0
0
0
59
0
0
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
9
17
0
0
0
% N
% Pro:
0
9
0
0
9
0
0
0
0
0
0
0
9
0
9
% P
% Gln:
9
0
34
0
0
34
0
9
0
9
9
0
0
0
0
% Q
% Arg:
9
9
0
9
9
0
9
0
50
17
0
9
9
9
9
% R
% Ser:
50
34
9
0
0
25
17
9
0
9
9
9
0
17
9
% S
% Thr:
17
9
0
0
0
9
0
0
0
42
0
0
9
0
0
% T
% Val:
0
0
9
9
0
0
0
9
0
0
9
0
34
9
9
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
42
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _