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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TAS2R38
All Species:
12.42
Human Site:
S219
Identified Species:
68.33
UniProt:
P59533
Number Species:
4
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59533
NP_789787.3
333
37892
S219
S
S
G
M
L
T
V
S
L
G
R
H
M
R
T
Chimpanzee
Pan troglodytes
Q697L5
333
37838
S219
S
S
G
M
L
T
V
S
L
G
R
H
M
R
T
Rhesus Macaque
Macaca mulatta
Q645T7
318
36681
R214
S
L
W
R
H
I
R
R
M
Q
L
S
A
T
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQA6
331
36948
S218
S
S
G
V
L
V
I
S
L
G
S
H
M
R
T
Rat
Rattus norvegicus
Q4VHE7
331
37214
S218
S
S
G
V
L
V
I
S
L
G
N
H
M
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
30.9
N.A.
N.A.
65.4
65.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
50.1
N.A.
N.A.
79.8
79.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
N.A.
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
N.A.
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
80
0
0
0
0
0
0
80
0
0
0
0
20
% G
% His:
0
0
0
0
20
0
0
0
0
0
0
80
0
0
0
% H
% Ile:
0
0
0
0
0
20
40
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
20
0
0
80
0
0
0
80
0
20
0
0
0
0
% L
% Met:
0
0
0
40
0
0
0
0
20
0
0
0
80
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% Q
% Arg:
0
0
0
20
0
0
20
20
0
0
40
0
0
80
0
% R
% Ser:
100
80
0
0
0
0
0
80
0
0
20
20
0
0
0
% S
% Thr:
0
0
0
0
0
40
0
0
0
0
0
0
0
20
80
% T
% Val:
0
0
0
40
0
40
40
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _