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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TAS2R46
All Species:
8.18
Human Site:
S216
Identified Species:
45
UniProt:
P59540
Number Species:
4
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59540
NP_795368.2
309
35523
S216
M
Q
L
H
G
K
G
S
Q
D
P
S
M
K
V
Chimpanzee
Pan troglodytes
Q646C0
309
35573
S216
M
Q
L
H
G
K
G
S
Q
D
P
S
M
K
V
Rhesus Macaque
Macaca mulatta
Q645T3
308
35334
S216
M
Q
L
R
D
K
G
S
Q
D
P
S
T
K
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7M721
295
33576
K203
L
L
I
Y
S
L
S
K
H
L
K
N
M
K
F
Rat
Rattus norvegicus
Q675B7
330
37340
P238
M
R
L
Y
G
K
G
P
H
N
P
S
A
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
85.4
N.A.
N.A.
48.2
42.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98
90.6
N.A.
N.A.
66.9
63
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
N.A.
N.A.
13.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
N.A.
N.A.
40
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
20
0
0
0
0
60
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% F
% Gly:
0
0
0
0
60
0
80
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
40
0
0
0
0
40
0
0
0
0
0
0
% H
% Ile:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
80
0
20
0
0
20
0
0
80
0
% K
% Leu:
20
20
80
0
0
20
0
0
0
20
0
0
0
0
0
% L
% Met:
80
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
20
0
20
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
20
0
0
80
0
0
0
0
% P
% Gln:
0
60
0
0
0
0
0
0
60
0
0
0
0
0
0
% Q
% Arg:
0
20
0
20
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
20
0
20
60
0
0
0
80
0
20
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _