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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FXYD4
All Species:
11.52
Human Site:
S66
Identified Species:
36.19
UniProt:
P59646
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59646
NP_775183.1
89
9373
S66
G
K
C
K
C
K
S
S
Q
K
Q
H
S
P
V
Chimpanzee
Pan troglodytes
XP_001155768
89
9373
S66
G
K
C
K
C
K
S
S
Q
K
Q
H
S
P
V
Rhesus Macaque
Macaca mulatta
XP_001109347
136
14464
S113
S
K
C
K
C
K
S
S
Q
K
Q
H
S
P
V
Dog
Lupus familis
XP_855497
89
9538
S67
G
K
C
K
C
K
F
S
Q
K
P
S
H
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61835
88
9508
F65
S
G
K
C
K
C
K
F
R
Q
K
P
S
H
R
Rat
Rattus norvegicus
Q63113
87
9065
R65
S
G
K
C
K
C
R
R
N
H
T
P
S
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521652
95
10484
N66
R
R
C
K
C
S
F
N
Q
K
P
R
A
P
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086408
94
10345
L64
R
R
C
R
C
N
N
L
N
Q
K
Q
R
A
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
47.7
60.6
N.A.
59.5
62.9
N.A.
32.6
N.A.
32.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
50.7
70.7
N.A.
71.9
74.1
N.A.
50.5
N.A.
53.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
6.6
6.6
N.A.
46.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
60
N.A.
26.6
13.3
N.A.
66.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
13
13
0
% A
% Cys:
0
0
75
25
75
25
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
25
13
0
0
0
0
0
0
0
% F
% Gly:
38
25
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
38
13
25
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
50
25
63
25
50
13
0
0
63
25
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
13
13
13
25
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
25
25
0
50
25
% P
% Gln:
0
0
0
0
0
0
0
0
63
25
38
13
0
0
0
% Q
% Arg:
25
25
0
13
0
0
13
13
13
0
0
13
13
0
13
% R
% Ser:
38
0
0
0
0
13
38
50
0
0
0
13
63
13
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _