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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FXYD4 All Species: 9.19
Human Site: T88 Identified Species: 28.89
UniProt: P59646 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P59646 NP_775183.1 89 9373 T88 I T P G S A T T C _ _ _ _ _ _
Chimpanzee Pan troglodytes XP_001155768 89 9373 T88 I T P G S A T T C _ _ _ _ _ _
Rhesus Macaque Macaca mulatta XP_001109347 136 14464 T135 I T P G S T T T C _ _ _ _ _ _
Dog Lupus familis XP_855497 89 9538
Cat Felis silvestris
Mouse Mus musculus Q61835 88 9508 N87 I T P G S A H N C _ _ _ _ _ _
Rat Rattus norvegicus Q63113 87 9065
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521652 95 10484 T88 T L I T S N A T E P Q K A E N
Chicken Gallus gallus
Frog Xenopus laevis NP_001086408 94 10345 A86 E N L I A S K A R G S Q K A E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 47.7 60.6 N.A. 59.5 62.9 N.A. 32.6 N.A. 32.9 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 50.7 70.7 N.A. 71.9 74.1 N.A. 50.5 N.A. 53.1 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 88.8 0 N.A. 77.7 0 N.A. 13.3 N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 88.8 0 N.A. 77.7 0 N.A. 13.3 N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 13 38 13 13 0 0 0 0 13 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 13 0 0 0 0 0 0 0 13 0 0 0 0 13 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 50 0 0 0 0 0 13 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % H
% Ile: 50 0 13 13 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 13 0 0 0 0 13 13 0 0 % K
% Leu: 0 13 13 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 0 0 0 13 0 13 0 0 0 0 0 0 13 % N
% Pro: 0 0 50 0 0 0 0 0 0 13 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 13 13 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 63 13 0 0 0 0 13 0 0 0 0 % S
% Thr: 13 50 0 13 0 13 38 50 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 50 50 50 50 50 50 % _