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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3S2
All Species:
31.21
Human Site:
S59
Identified Species:
49.05
UniProt:
P59780
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P59780
NP_005820.1
193
22017
S59
G
G
S
L
I
G
G
S
D
Y
K
L
I
Y
R
Chimpanzee
Pan troglodytes
XP_001167960
205
23380
S59
G
G
S
L
I
G
G
S
D
Y
K
L
I
Y
R
Rhesus Macaque
Macaca mulatta
XP_001094426
205
23394
S59
G
G
S
L
I
G
G
S
D
Y
K
L
I
Y
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TN05
154
18422
G43
I
Q
T
V
L
S
R
G
H
R
T
S
S
F
I
Rat
Rattus norvegicus
P62744
142
16999
L31
D
D
D
E
K
Q
K
L
I
E
E
V
H
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505884
170
18952
R43
S
D
N
K
L
I
Y
R
H
Y
A
T
L
Y
F
Chicken
Gallus gallus
NP_001006586
193
21787
S59
G
G
L
L
I
G
G
S
D
N
K
L
I
Y
R
Frog
Xenopus laevis
NP_001088897
193
22046
S59
G
G
S
L
I
G
G
S
D
Y
K
L
I
Y
R
Zebra Danio
Brachydanio rerio
NP_001002539
192
21893
S59
G
G
S
L
I
G
G
S
D
Y
K
L
I
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_536793
191
21692
S59
G
G
S
L
I
G
G
S
D
Y
K
L
I
Y
R
Honey Bee
Apis mellifera
XP_397320
191
21930
S59
G
G
S
L
I
G
G
S
D
Y
K
L
I
Y
R
Nematode Worm
Caenorhab. elegans
NP_740780
192
22090
N59
G
G
T
L
I
D
G
N
D
Y
R
L
I
Y
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50016
132
15996
V21
T
R
L
A
K
Y
Y
V
P
L
E
D
S
E
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47064
194
21919
E71
N
N
D
E
V
N
N
E
D
I
Q
I
I
Y
K
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
K32
D
E
E
K
I
K
L
K
G
E
I
H
R
L
V
Conservation
Percent
Protein Identity:
100
94.1
94.1
N.A.
N.A.
31.6
33.1
N.A.
75.1
84.4
84.9
90.6
N.A.
74.6
76.6
72
N.A.
Protein Similarity:
100
94.1
94.1
N.A.
N.A.
53.8
49.7
N.A.
81.3
92.7
93.7
96.8
N.A.
87.5
89.1
87.5
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
0
0
N.A.
13.3
86.6
100
100
N.A.
100
100
73.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
26.6
13.3
N.A.
33.3
86.6
100
100
N.A.
100
100
93.3
N.A.
Percent
Protein Identity:
N.A.
30.5
N.A.
N.A.
38.1
29.5
Protein Similarity:
N.A.
45
N.A.
N.A.
58.7
47.6
P-Site Identity:
N.A.
0
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
46.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
14
14
0
0
7
0
0
67
0
0
7
0
0
0
% D
% Glu:
0
7
7
14
0
0
0
7
0
14
14
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% F
% Gly:
60
60
0
0
0
54
60
7
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
14
0
0
7
7
0
0
% H
% Ile:
7
0
0
0
67
7
0
0
7
7
7
7
67
0
7
% I
% Lys:
0
0
0
14
14
7
7
7
0
0
54
0
0
0
14
% K
% Leu:
0
0
14
60
14
0
7
7
0
7
0
60
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
7
0
0
7
7
7
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
7
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
7
0
0
0
0
7
7
0
7
7
0
7
0
60
% R
% Ser:
7
0
47
0
0
7
0
54
0
0
0
7
14
0
0
% S
% Thr:
7
0
14
0
0
0
0
0
0
0
7
7
0
0
0
% T
% Val:
0
0
0
7
7
0
0
7
0
0
0
7
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
14
0
0
60
0
0
0
74
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _