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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPX6 All Species: 1.21
Human Site: S131 Identified Species: 2.42
UniProt: P59796 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P59796 NP_874360.1 221 24971 S131 P G S G F V P S F Q L F E K G
Chimpanzee Pan troglodytes Q0EFA0 201 21781 L123 N G A G A H T L F A F L R E A
Rhesus Macaque Macaca mulatta NP_001152830 221 25020 N131 P G S G F V P N F Q L F E K G
Dog Lupus familis XP_545450 154 17353 T92 L K N S C P P T S D L L G S S
Cat Felis silvestris
Mouse Mus musculus Q91WR8 221 24827 N131 P G G G Y V P N F Q L F E K G
Rat Rattus norvegicus Q64625 221 24943 N131 P G G G F V P N F Q L F E K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001156704 219 24474 N129 P G G G F V P N F Q L F Q K G
Frog Xenopus laevis NP_001085319 233 26458 N131 P G G N F I P N F Q L F E K G
Zebra Danio Brachydanio rerio NP_001131027 222 24765 N129 P G N G F V P N F Q L F E K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95003 224 25537 H131 P G N G W T P H Q E L H I Y G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O48646 232 25566 F163 F K A E Y P I F D K V D V N G
Baker's Yeast Sacchar. cerevisiae P38143 162 18388 N100 I M K K I D V N G S N A D S V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38 94.1 59.7 N.A. 71 73.3 N.A. N.A. 60.1 51 54.9 N.A. N.A. N.A. 34.3 N.A.
Protein Similarity: 100 50.2 95.4 63.7 N.A. 81.4 81.9 N.A. N.A. 74.6 65.2 69.3 N.A. N.A. N.A. 53.1 N.A.
P-Site Identity: 100 20 93.3 13.3 N.A. 80 86.6 N.A. N.A. 80 73.3 86.6 N.A. N.A. N.A. 40 N.A.
P-Site Similarity: 100 33.3 100 26.6 N.A. 93.3 93.3 N.A. N.A. 93.3 86.6 100 N.A. N.A. N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.7 30.7 N.A.
Protein Similarity: N.A. N.A. N.A. 49.1 46.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 9 0 0 0 0 9 0 9 0 0 9 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 9 9 0 9 9 0 0 % D
% Glu: 0 0 0 9 0 0 0 0 0 9 0 0 50 9 0 % E
% Phe: 9 0 0 0 50 0 0 9 67 0 9 59 0 0 0 % F
% Gly: 0 75 34 67 0 0 0 0 9 0 0 0 9 0 75 % G
% His: 0 0 0 0 0 9 0 9 0 0 0 9 0 0 0 % H
% Ile: 9 0 0 0 9 9 9 0 0 0 0 0 9 0 0 % I
% Lys: 0 17 9 9 0 0 0 0 0 9 0 0 0 59 0 % K
% Leu: 9 0 0 0 0 0 0 9 0 0 75 17 0 0 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 25 9 0 0 0 59 0 0 9 0 0 9 0 % N
% Pro: 67 0 0 0 0 17 75 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 9 59 0 0 9 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 0 17 9 0 0 0 9 9 9 0 0 0 17 9 % S
% Thr: 0 0 0 0 0 9 9 9 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 50 9 0 0 0 9 0 9 0 9 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 17 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _