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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPX6 All Species: 19.39
Human Site: Y214 Identified Species: 38.79
UniProt: P59796 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P59796 NP_874360.1 221 24971 Y214 V K S D I L E Y L K Q F N T H
Chimpanzee Pan troglodytes Q0EFA0 201 21781 L193 I E P D I E A L L S Q G P S C
Rhesus Macaque Macaca mulatta NP_001152830 221 25020 Y214 V K S D I L E Y L K Q F N A H
Dog Lupus familis XP_545450 154 17353
Cat Felis silvestris
Mouse Mus musculus Q91WR8 221 24827 Y214 V Q S D I M E Y L N Q T S T Q
Rat Rattus norvegicus Q64625 221 24943 Y214 V Q S D I M E Y L N Q T R T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001156704 219 24474 Y212 V K N D I I A Y M R Q Q R G Q
Frog Xenopus laevis NP_001085319 233 26458 Y215 V R R E I V S Y I K L Q Q G T
Zebra Danio Brachydanio rerio NP_001131027 222 24765 Y213 V R A D I L K Y F H Q L L Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95003 224 25537 F214 H G D V V T P F I E Q L L A E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O48646 232 25566 D223 S P L S I E K D V K K L L G V
Baker's Yeast Sacchar. cerevisiae P38143 162 18388
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38 94.1 59.7 N.A. 71 73.3 N.A. N.A. 60.1 51 54.9 N.A. N.A. N.A. 34.3 N.A.
Protein Similarity: 100 50.2 95.4 63.7 N.A. 81.4 81.9 N.A. N.A. 74.6 65.2 69.3 N.A. N.A. N.A. 53.1 N.A.
P-Site Identity: 100 26.6 93.3 0 N.A. 60 60 N.A. N.A. 40 26.6 40 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 46.6 93.3 0 N.A. 80 73.3 N.A. N.A. 66.6 53.3 60 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.7 30.7 N.A.
Protein Similarity: N.A. N.A. N.A. 49.1 46.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 17 0 0 0 0 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 9 59 0 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 9 0 17 34 0 0 9 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 9 9 0 0 17 0 0 0 % F
% Gly: 0 9 0 0 0 0 0 0 0 0 0 9 0 25 0 % G
% His: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 17 % H
% Ile: 9 0 0 0 75 9 0 0 17 0 0 0 0 0 0 % I
% Lys: 0 25 0 0 0 0 17 0 0 34 9 0 0 0 0 % K
% Leu: 0 0 9 0 0 25 0 9 42 0 9 25 25 0 0 % L
% Met: 0 0 0 0 0 17 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 17 0 0 17 0 0 % N
% Pro: 0 9 9 0 0 0 9 0 0 0 0 0 9 0 0 % P
% Gln: 0 17 0 0 0 0 0 0 0 0 67 17 9 9 25 % Q
% Arg: 0 17 9 0 0 0 0 0 0 9 0 0 17 0 0 % R
% Ser: 9 0 34 9 0 0 9 0 0 9 0 0 9 9 0 % S
% Thr: 0 0 0 0 0 9 0 0 0 0 0 17 0 25 17 % T
% Val: 59 0 0 9 9 9 0 0 9 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _