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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPX6 All Species: 11.21
Human Site: Y53 Identified Species: 22.42
UniProt: P59796 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P59796 NP_874360.1 221 24971 Y53 L T L N G E E Y I Q F K Q F A
Chimpanzee Pan troglodytes Q0EFA0 201 21781 R63 Q M N E L Q R R L G P R G L V
Rhesus Macaque Macaca mulatta NP_001152830 221 25020 Y53 L T L N S E E Y I Q F K Q F A
Dog Lupus familis XP_545450 154 17353 N35 V V L G F P C N Q F G K Q E P
Cat Felis silvestris
Mouse Mus musculus Q91WR8 221 24827 F53 N T I D G G G F V N F Q Q Y A
Rat Rattus norvegicus Q64625 221 24943 Y53 N T L D G G E Y V Q F Q Q Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001156704 219 24474 F54 D G D E Y I P F R K Y A G K M
Frog Xenopus laevis NP_001085319 233 26458 F53 T T L D G S Q F I P F K A Y Q
Zebra Danio Brachydanio rerio NP_001131027 222 24765 P53 I N G T Q F I P F S H Y A G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95003 224 25537 T54 E T L Q G E Y T D L S Q Y R G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O48646 232 25566 L88 A K G N D V D L S I Y K G K V
Baker's Yeast Sacchar. cerevisiae P38143 162 18388 Y43 K C G F T P Q Y K E L E E L Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 38 94.1 59.7 N.A. 71 73.3 N.A. N.A. 60.1 51 54.9 N.A. N.A. N.A. 34.3 N.A.
Protein Similarity: 100 50.2 95.4 63.7 N.A. 81.4 81.9 N.A. N.A. 74.6 65.2 69.3 N.A. N.A. N.A. 53.1 N.A.
P-Site Identity: 100 0 93.3 20 N.A. 33.3 60 N.A. N.A. 0 40 0 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 100 20 93.3 26.6 N.A. 73.3 86.6 N.A. N.A. 20 66.6 6.6 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 32.7 30.7 N.A.
Protein Similarity: N.A. N.A. N.A. 49.1 46.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 0 0 0 9 17 0 34 % A
% Cys: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 25 9 0 9 0 9 0 0 0 0 0 0 % D
% Glu: 9 0 0 17 0 25 25 0 0 9 0 9 9 9 0 % E
% Phe: 0 0 0 9 9 9 0 25 9 9 42 0 0 17 0 % F
% Gly: 0 9 25 9 42 17 9 0 0 9 9 0 25 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 9 0 9 0 0 9 9 0 25 9 0 0 0 0 0 % I
% Lys: 9 9 0 0 0 0 0 0 9 9 0 42 0 17 9 % K
% Leu: 17 0 50 0 9 0 0 9 9 9 9 0 0 17 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 17 9 9 25 0 0 0 9 0 9 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 17 9 9 0 9 9 0 0 0 9 % P
% Gln: 9 0 0 9 9 9 17 0 9 25 0 25 42 0 9 % Q
% Arg: 0 0 0 0 0 0 9 9 9 0 0 9 0 9 0 % R
% Ser: 0 0 0 0 9 9 0 0 9 9 9 0 0 0 0 % S
% Thr: 9 50 0 9 9 0 0 9 0 0 0 0 0 0 0 % T
% Val: 9 9 0 0 0 9 0 0 17 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 9 34 0 0 17 9 9 25 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _