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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF445 All Species: 10.61
Human Site: S495 Identified Species: 46.67
UniProt: P59923 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P59923 NP_852466.1 1031 118963 S495 S D C G R T F S H S S H L A Y
Chimpanzee Pan troglodytes XP_517010 643 73098 S122 V Q L H N P E S G E E A V A L
Rhesus Macaque Macaca mulatta XP_001114939 1031 119075 S495 S D C G R T F S H S S H L A Y
Dog Lupus familis XP_848684 1015 117611 S487 S D C G R T F S H S S H L A C
Cat Felis silvestris
Mouse Mus musculus Q8R2V3 986 114756 S465 E H R Q P S Y S E E G L F Q C
Rat Rattus norvegicus XP_236726 977 113683 Q456 E Y Q R Y Y S Q G S L F K C R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.7 97.9 78.6 N.A. 59.6 60.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 62.3 98.7 86.5 N.A. 72.9 72.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 93.3 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 93.3 N.A. 20 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 17 0 67 0 % A
% Cys: 0 0 50 0 0 0 0 0 0 0 0 0 0 17 34 % C
% Asp: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 34 0 0 0 0 0 17 0 17 34 17 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 50 0 0 0 0 17 17 0 0 % F
% Gly: 0 0 0 50 0 0 0 0 34 0 17 0 0 0 0 % G
% His: 0 17 0 17 0 0 0 0 50 0 0 50 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % K
% Leu: 0 0 17 0 0 0 0 0 0 0 17 17 50 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 17 17 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 17 17 17 0 0 0 17 0 0 0 0 0 17 0 % Q
% Arg: 0 0 17 17 50 0 0 0 0 0 0 0 0 0 17 % R
% Ser: 50 0 0 0 0 17 17 84 0 67 50 0 0 0 0 % S
% Thr: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % T
% Val: 17 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 0 0 17 17 17 0 0 0 0 0 0 0 34 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _