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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CD81 All Species: 21.82
Human Site: S177 Identified Species: 48
UniProt: P60033 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P60033 NP_004347.1 236 25809 S177 L K N N L C P S G S N I I S N
Chimpanzee Pan troglodytes Q7YQL0 244 26954 S168 L E H G I P P S C C M N E T D
Rhesus Macaque Macaca mulatta XP_001093228 236 25740 S177 L K N N L C P S G S N I I S N
Dog Lupus familis XP_854381 244 26214 S185 L K N S L C P S G S N V I S N
Cat Felis silvestris
Mouse Mus musculus P35762 236 25810 S177 L R N T L C P S G G N I L T P
Rat Rattus norvegicus Q62745 236 25870 S177 L R N S L C P S S S N S F T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520001 205 22554 L150 T C P E K D V L E A L T T K S
Chicken Gallus gallus NP_001025510 166 18316 L114 K D L L K G L L K R E E N C H
Frog Xenopus laevis Q6DCQ3 239 26764 C177 C M E N S Q D C G H N S T S L
Zebra Danio Brachydanio rerio Q6GMK6 239 26765 C177 C Q E H Y T E C G R N T T N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001140831 236 25886 S177 L R N S L C P S S S N S F T Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.4 98.3 86 N.A. 91.9 93.2 N.A. 37.7 55.9 30.1 29.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 45.9 99.1 90.5 N.A. 97.4 97 N.A. 55.9 62.2 48.9 51.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 100 86.6 N.A. 60 53.3 N.A. 0 0 26.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 53.3 100 100 N.A. 80 73.3 N.A. 13.3 6.6 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. 93.2 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 97.4 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 53.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 73.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % A
% Cys: 19 10 0 0 0 55 0 19 10 10 0 0 0 10 0 % C
% Asp: 0 10 0 0 0 10 10 0 0 0 0 0 0 0 10 % D
% Glu: 0 10 19 10 0 0 10 0 10 0 10 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % F
% Gly: 0 0 0 10 0 10 0 0 55 10 0 0 0 0 0 % G
% His: 0 0 10 10 0 0 0 0 0 10 0 0 0 0 10 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 28 28 0 0 % I
% Lys: 10 28 0 0 19 0 0 0 10 0 0 0 0 10 0 % K
% Leu: 64 0 10 10 55 0 10 19 0 0 10 0 10 0 10 % L
% Met: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 55 28 0 0 0 0 0 0 73 10 10 10 28 % N
% Pro: 0 0 10 0 0 10 64 0 0 0 0 0 0 0 10 % P
% Gln: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 19 % Q
% Arg: 0 28 0 0 0 0 0 0 0 19 0 0 0 0 0 % R
% Ser: 0 0 0 28 10 0 0 64 19 46 0 28 0 37 10 % S
% Thr: 10 0 0 10 0 10 0 0 0 0 0 19 28 37 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _