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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC61G All Species: 27.88
Human Site: S18 Identified Species: 68.15
UniProt: P60059 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P60059 NP_001012474.1 68 7741 S18 S R Q F V K D S I R L V K R C
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q66KU2 68 7753 S18 S R Q F V K D S I R L V K R C
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V668 68 7546 S18 G R A F A K D S I R L V K R C
Honey Bee Apis mellifera XP_001120892 68 7688 S18 G R Q F A K D S I R L I K R C
Nematode Worm Caenorhab. elegans Q19967 68 7743 S18 A R Q F S K D S Y R L V K R C
Sea Urchin Strong. purpuratus XP_797211 68 7692 S18 A K Q F A K D S I R L V K R C
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001150911 69 7677 S18 L R E F A K D S I R L V K R C
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SW34 69 7719 S18 L R D F A K D S I R L V K R C
Baker's Yeast Sacchar. cerevisiae P35179 80 8925 G32 P V E F V R E G T Q F L A K C
Red Bread Mold Neurospora crassa Q9C2D4 70 7791 G19 P R E F L K D G I Q F I K K C
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 98.5 N.A. N.A. 85.2 85.2 85.2 86.7
Protein Similarity: 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 98.5 N.A. N.A. 92.6 89.7 89.7 92.6
P-Site Identity: 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 100 N.A. N.A. 80 80 80 80
P-Site Similarity: 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 100 N.A. N.A. 80 86.6 86.6 93.3
Percent
Protein Identity: N.A. 73.9 N.A. 71 38.7 51.4
Protein Similarity: N.A. 81.1 N.A. 79.7 55 74.2
P-Site Identity: N.A. 80 N.A. 80 20 46.6
P-Site Similarity: N.A. 86.6 N.A. 80 60 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 10 0 50 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % C
% Asp: 0 0 10 0 0 0 90 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 30 0 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 100 0 0 0 0 0 0 20 0 0 0 0 % F
% Gly: 20 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 80 0 0 20 0 0 0 % I
% Lys: 0 10 0 0 0 90 0 0 0 0 0 0 90 20 0 % K
% Leu: 20 0 0 0 10 0 0 0 0 0 80 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 50 0 0 0 0 0 0 20 0 0 0 0 0 % Q
% Arg: 0 80 0 0 0 10 0 0 0 80 0 0 0 80 0 % R
% Ser: 20 0 0 0 10 0 0 80 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 10 0 0 30 0 0 0 0 0 0 70 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _