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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPI1
All Species:
31.52
Human Site:
S195
Identified Species:
46.22
UniProt:
P60174
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60174
NP_000356.1
249
26669
S195
K
L
R
G
W
L
K
S
N
V
S
D
A
V
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
P15426
249
26692
S195
K
L
R
G
W
L
K
S
N
V
S
E
A
V
A
Dog
Lupus familis
XP_534904
249
26696
S195
K
L
R
G
W
L
K
S
N
V
S
D
A
V
A
Cat
Felis silvestris
Mouse
Mus musculus
P17751
249
26694
S195
K
L
R
G
W
L
K
S
N
V
N
D
G
V
A
Rat
Rattus norvegicus
P48500
249
26830
C195
K
L
R
G
W
L
K
C
N
V
S
E
G
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P00940
248
26602
S194
K
L
R
G
W
L
K
S
H
V
S
D
A
V
A
Frog
Xenopus laevis
Q7ZWN5
248
26743
T194
K
L
R
E
W
V
K
T
N
V
S
E
G
V
A
Zebra Danio
Brachydanio rerio
Q90XG0
248
26809
T194
K
L
R
Q
W
L
K
T
N
V
S
E
A
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29613
247
26607
D193
F
L
R
Q
W
L
S
D
N
I
S
K
E
V
S
Honey Bee
Apis mellifera
NP_001090623
247
26880
K193
K
L
R
N
W
F
S
K
N
V
N
Q
T
V
A
Nematode Worm
Caenorhab. elegans
Q10657
247
26556
E193
W
I
R
A
F
L
K
E
K
V
S
P
A
V
A
Sea Urchin
Strong. purpuratus
NP_001116981
250
26829
E195
N
L
R
S
W
L
T
E
H
V
N
A
A
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P12863
253
27006
T195
S
L
R
D
W
L
K
T
N
A
S
P
E
V
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SKP6
315
33327
K254
A
V
R
G
W
L
K
K
N
V
S
E
E
V
A
Baker's Yeast
Sacchar. cerevisiae
P00942
248
26777
S194
S
I
R
K
F
L
A
S
K
L
G
D
K
A
A
Red Bread Mold
Neurospora crassa
Q7S2Z9
248
27215
Q194
A
I
R
S
W
L
K
Q
N
V
S
D
K
V
A
Conservation
Percent
Protein Identity:
100
N.A.
99.1
98.3
N.A.
95.9
94.3
N.A.
N.A.
89.5
83.5
82.7
N.A.
64.2
63
61.8
63.2
Protein Similarity:
100
N.A.
100
99.1
N.A.
97.5
96.3
N.A.
N.A.
91.9
91.5
87.9
N.A.
75
76.3
73.4
76
P-Site Identity:
100
N.A.
93.3
100
N.A.
86.6
80
N.A.
N.A.
93.3
66.6
80
N.A.
46.6
53.3
53.3
53.3
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
N.A.
100
86.6
93.3
N.A.
60
60
66.6
66.6
Percent
Protein Identity:
N.A.
62
N.A.
50.1
53.4
57.8
Protein Similarity:
N.A.
75.1
N.A.
58.7
67.8
69.4
P-Site Identity:
N.A.
60
N.A.
66.6
33.3
66.6
P-Site Similarity:
N.A.
66.6
N.A.
80
53.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
7
0
0
7
0
0
7
0
7
44
7
94
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
7
0
0
0
38
0
0
0
% D
% Glu:
0
0
0
7
0
0
0
13
0
0
0
32
19
0
0
% E
% Phe:
7
0
0
0
13
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
44
0
0
0
0
0
0
7
0
19
0
0
% G
% His:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% H
% Ile:
0
19
0
0
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
57
0
0
7
0
0
75
13
13
0
0
7
13
0
0
% K
% Leu:
0
75
0
0
0
88
0
0
0
7
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
0
0
0
0
75
0
19
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% P
% Gln:
0
0
0
13
0
0
0
7
0
0
0
7
0
0
0
% Q
% Arg:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
0
0
13
0
0
13
38
0
0
75
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
7
19
0
0
0
0
7
0
0
% T
% Val:
0
7
0
0
0
7
0
0
0
82
0
0
0
94
0
% V
% Trp:
7
0
0
0
88
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _