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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3E
All Species:
0
Human Site:
S106
Identified Species:
0
UniProt:
P60228
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60228
NP_001559.1
445
52221
S106
E
T
T
R
Q
M
Q
S
T
R
D
G
R
M
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090244
396
46427
Dog
Lupus familis
XP_860062
352
41339
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
XP_002727410
445
52210
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505745
451
52629
Chicken
Gallus gallus
Q5ZLA5
445
52117
Frog
Xenopus laevis
Q3B8M3
446
52223
Zebra Danio
Brachydanio rerio
Q1LUA8
446
52584
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77410
435
51144
Honey Bee
Apis mellifera
XP_623637
451
52726
Nematode Worm
Caenorhab. elegans
O61820
432
50701
Sea Urchin
Strong. purpuratus
XP_001193661
398
46711
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S519
443
51032
Conservation
Percent
Protein Identity:
100
N.A.
88.9
79
N.A.
N.A.
99
N.A.
92.9
97.5
95.7
93.7
N.A.
59
58.9
49.4
63.3
Protein Similarity:
100
N.A.
88.9
79
N.A.
N.A.
99
N.A.
93.7
99.5
98.4
98.2
N.A.
76.1
76.2
69.4
73.7
P-Site Identity:
100
N.A.
0
0
N.A.
N.A.
0
N.A.
0
0
0
0
N.A.
0
0
0
0
P-Site Similarity:
100
N.A.
0
0
N.A.
N.A.
0
N.A.
0
0
0
0
N.A.
0
0
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
63.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% D
% Glu:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% L
% Met:
0
0
0
0
0
100
0
0
0
0
0
0
0
100
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
100
0
100
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
100
0
0
0
0
0
100
0
0
100
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% S
% Thr:
0
100
100
0
0
0
0
0
100
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _