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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPP4C All Species: 53.03
Human Site: S209 Identified Species: 83.33
UniProt: P60510 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P60510 NP_002711.1 307 35080 S209 D T T G W G V S P R G A G Y L
Chimpanzee Pan troglodytes XP_001148385 265 30391 C193 V P H D G P M C D L L W S D P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_858953 324 36761 S226 D T T G W G V S P R G A G Y L
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q5BJ92 307 35049 S209 D T T G W G V S P R G A G Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505222 306 34933 S208 D T T G W G V S P R G A G Y L
Chicken Gallus gallus P48463 309 35545 S212 D R G G W G I S P R G A G Y T
Frog Xenopus laevis Q6IP91 307 35104 S209 D T T G W G V S P R G A G Y L
Zebra Danio Brachydanio rerio A9JRC7 307 35078 S209 D T T G W G V S P R G A G Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76932 307 35323 S209 D Q T G W G V S P R G A G Y L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XW79 333 37341 S235 G N V G W G L S P R G A G Y L
Sea Urchin Strong. purpuratus XP_799172 307 35031 S209 D T Q G W G V S P R G A G Y L
Poplar Tree Populus trichocarpa XP_002317353 305 34758 S207 I V D G W G L S P R G A G F L
Maize Zea mays NP_001170721 307 34933 S209 T V D G W G L S P R G A G F L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P48528 305 34707 S207 I V D G W G L S P R G A G F L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48580 327 37273 S230 D R C G W G I S P R G A G Y T
Conservation
Percent
Protein Identity: 100 86.3 N.A. 94.7 N.A. N.A. 99.6 N.A. 91.2 66 99 98 N.A. 91.5 N.A. 74.7 93.4
Protein Similarity: 100 86.3 N.A. 94.7 N.A. N.A. 99.6 N.A. 92.5 81.2 99.6 99.6 N.A. 96.4 N.A. 82.5 97
P-Site Identity: 100 0 N.A. 100 N.A. N.A. 100 N.A. 100 73.3 100 100 N.A. 93.3 N.A. 73.3 93.3
P-Site Similarity: 100 6.6 N.A. 100 N.A. N.A. 100 N.A. 100 80 100 100 N.A. 93.3 N.A. 80 93.3
Percent
Protein Identity: 82 81.4 N.A. 82 N.A. 60.8
Protein Similarity: 89.9 90.8 N.A. 90.5 N.A. 75.8
P-Site Identity: 66.6 66.6 N.A. 66.6 N.A. 73.3
P-Site Similarity: 80 80 N.A. 80 N.A. 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 94 0 0 0 % A
% Cys: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 67 0 20 7 0 0 0 0 7 0 0 0 0 7 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % F
% Gly: 7 0 7 94 7 94 0 0 0 0 94 0 94 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 14 0 0 0 0 0 14 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 27 0 0 7 7 0 0 0 80 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 7 0 0 0 7 0 0 94 0 0 0 0 0 7 % P
% Gln: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 14 0 0 0 0 0 0 0 94 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 94 0 0 0 0 7 0 0 % S
% Thr: 7 47 47 0 0 0 0 0 0 0 0 0 0 0 14 % T
% Val: 7 20 7 0 0 0 54 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 94 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 74 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _