KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYL6
All Species:
38.48
Human Site:
T121
Identified Species:
94.07
UniProt:
P60660
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60660
NP_066299.2
151
16930
T121
V
T
L
G
E
K
M
T
E
E
E
V
E
M
L
Chimpanzee
Pan troglodytes
XP_001153433
152
17042
T122
V
T
L
G
E
K
M
T
E
E
E
V
E
M
L
Rhesus Macaque
Macaca mulatta
XP_001105712
151
16939
T121
V
T
L
G
E
K
M
T
E
E
E
V
E
M
L
Dog
Lupus familis
XP_531631
160
17940
T130
V
T
L
G
E
K
M
T
E
E
E
V
E
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI43
207
22730
T177
T
T
L
G
E
K
M
T
E
E
E
V
E
T
V
Rat
Rattus norvegicus
Q64119
151
16957
T121
V
T
L
G
E
K
M
T
E
E
E
V
E
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P02607
151
16969
T121
V
T
L
G
E
K
M
T
E
E
E
V
E
Q
L
Frog
Xenopus laevis
NP_001084714
151
17030
T121
I
S
L
G
E
K
L
T
E
D
E
V
E
T
L
Zebra Danio
Brachydanio rerio
NP_001005955
151
16919
T121
T
T
L
G
E
K
M
T
E
E
E
V
E
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54357
147
16595
T117
T
T
L
G
E
K
L
T
D
E
E
V
E
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
98.6
91.2
N.A.
58.4
96
N.A.
N.A.
89.4
73.5
82.7
N.A.
53.6
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
98.6
92.5
N.A.
66.1
98
N.A.
N.A.
94.6
87.4
93.3
N.A.
70.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
80
100
N.A.
N.A.
93.3
66.6
86.6
N.A.
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
100
N.A.
N.A.
93.3
93.3
86.6
N.A.
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
100
0
0
0
90
90
100
0
100
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
100
0
0
0
20
0
0
0
0
0
0
0
90
% L
% Met:
0
0
0
0
0
0
80
0
0
0
0
0
0
50
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
30
90
0
0
0
0
0
100
0
0
0
0
0
30
0
% T
% Val:
60
0
0
0
0
0
0
0
0
0
0
100
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _