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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTB All Species: 40.3
Human Site: S265 Identified Species: 98.52
UniProt: P60709 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P60709 NP_001092.1 375 41737 S265 P E A L F Q P S F L G M E S C
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850617 375 41748 S265 P E A L F Q P S F L S M E S C
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P60711 375 41718 S265 P E A L F Q P S F L G M E S C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P53478 376 41817 S266 P E A I F Q P S F L G M E S C
Frog Xenopus laevis O93400 375 41748 S265 P E A L F Q P S F L G M E S C
Zebra Danio Brachydanio rerio Q7ZVI7 375 41748 S265 P E A L F Q P S F L G M E S C
Tiger Blowfish Takifugu rubipres P53485 375 41748 S265 P E A L F Q P S F L G M E S C
Fruit Fly Dros. melanogaster P10987 376 41803 S266 P E A L F Q P S F L G M E A C
Honey Bee Apis mellifera XP_393368 376 41787 S266 P E A L F Q P S F L G M E A C
Nematode Worm Caenorhab. elegans P10984 376 41759 S266 P E A L F Q P S F L G M E S A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 99.7 N.A. N.A. 100 N.A. N.A. 98.9 99.4 98.9 98.9 97.8 97.8 97.8 N.A.
Protein Similarity: 100 N.A. N.A. 99.7 N.A. N.A. 100 N.A. N.A. 99.7 100 99.7 99.7 99.7 99.7 99.4 N.A.
P-Site Identity: 100 N.A. N.A. 93.3 N.A. N.A. 100 N.A. N.A. 93.3 100 100 100 93.3 93.3 93.3 N.A.
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. N.A. 100 N.A. N.A. 100 100 100 100 100 100 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 100 0 0 0 0 0 0 0 0 0 0 20 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 100 0 0 0 0 0 0 0 0 0 0 100 0 0 % E
% Phe: 0 0 0 0 100 0 0 0 100 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 90 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 90 0 0 0 0 0 100 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 100 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 10 0 0 80 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _