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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTB
All Species:
40.91
Human Site:
Y294
Identified Species:
100
UniProt:
P60709
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60709
NP_001092.1
375
41737
Y294
V
D
I
R
K
D
L
Y
A
N
T
V
L
S
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850617
375
41748
Y294
V
D
I
R
K
D
L
Y
A
N
T
V
L
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P60711
375
41718
Y294
V
D
I
R
K
D
L
Y
A
N
T
V
L
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P53478
376
41817
Y295
V
D
I
R
K
D
L
Y
A
N
T
V
L
S
G
Frog
Xenopus laevis
O93400
375
41748
Y294
V
D
I
R
K
D
L
Y
A
N
T
V
L
S
G
Zebra Danio
Brachydanio rerio
Q7ZVI7
375
41748
Y294
V
D
I
R
K
D
L
Y
A
N
T
V
L
S
G
Tiger Blowfish
Takifugu rubipres
P53485
375
41748
Y294
V
D
I
R
K
D
L
Y
A
N
T
V
L
S
G
Fruit Fly
Dros. melanogaster
P10987
376
41803
Y295
V
D
I
R
K
D
L
Y
A
N
T
V
L
S
G
Honey Bee
Apis mellifera
XP_393368
376
41787
Y295
V
D
I
R
K
D
L
Y
A
N
T
V
L
S
G
Nematode Worm
Caenorhab. elegans
P10984
376
41759
Y295
I
D
I
R
K
D
L
Y
A
N
T
V
L
S
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.7
N.A.
N.A.
100
N.A.
N.A.
98.9
99.4
98.9
98.9
97.8
97.8
97.8
N.A.
Protein Similarity:
100
N.A.
N.A.
99.7
N.A.
N.A.
100
N.A.
N.A.
99.7
100
99.7
99.7
99.7
99.7
99.4
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
100
100
100
100
100
100
93.3
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
100
100
100
100
100
100
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
100
0
0
0
100
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
100
0
0
0
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% T
% Val:
90
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _