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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAC3
All Species:
53.03
Human Site:
Y154
Identified Species:
89.74
UniProt:
P60763
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60763
NP_005043.1
192
21379
Y154
R
E
I
G
S
V
K
Y
L
E
C
S
A
L
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113336
199
21967
Y161
R
E
I
G
S
V
K
Y
L
E
C
S
A
L
T
Dog
Lupus familis
XP_855587
192
21504
Y154
K
E
I
G
A
V
K
Y
L
E
C
S
A
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q05144
192
21422
Y154
K
D
I
D
S
V
K
Y
L
E
C
S
A
L
T
Rat
Rattus norvegicus
Q6RUV5
192
21432
Y154
K
E
I
G
A
V
K
Y
L
E
C
S
A
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513560
192
21428
Y154
K
E
I
H
S
V
K
Y
L
E
C
S
A
L
T
Chicken
Gallus gallus
Q90694
191
21254
Y154
R
D
L
K
A
V
K
Y
V
E
C
S
A
L
T
Frog
Xenopus laevis
NP_001084224
192
21460
Y154
K
E
I
G
A
V
K
Y
L
E
C
S
A
L
T
Zebra Danio
Brachydanio rerio
NP_001002754
192
21380
Y154
R
E
I
G
A
V
K
Y
L
E
C
S
A
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40792
192
21335
Y154
K
E
I
G
A
V
K
Y
L
E
C
S
A
L
T
Honey Bee
Apis mellifera
XP_623951
192
21451
Y154
K
E
I
G
A
V
K
Y
L
E
C
S
A
L
T
Nematode Worm
Caenorhab. elegans
Q03206
191
21436
Y154
K
E
I
K
A
V
K
Y
L
E
C
S
A
L
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38912
198
21710
E157
I
G
A
P
A
Y
I
E
C
S
A
K
T
Q
Q
Baker's Yeast
Sacchar. cerevisiae
P19073
191
21304
Y154
R
E
L
K
A
V
K
Y
V
E
C
S
A
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91.9
92.1
N.A.
88
92.7
N.A.
88.5
69.2
92.7
97.9
N.A.
89
89
81.7
N.A.
Protein Similarity:
100
N.A.
92.4
96.8
N.A.
95.3
97.4
N.A.
94.2
80.7
97.4
99.4
N.A.
94.7
95.8
90.6
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
80
86.6
N.A.
86.6
66.6
86.6
93.3
N.A.
86.6
86.6
80
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
100
N.A.
93.3
93.3
100
100
N.A.
100
100
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
60.6
69.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
73.2
82.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
72
0
0
0
0
0
8
0
93
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
93
0
0
0
0
% C
% Asp:
0
15
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
79
0
0
0
0
0
8
0
93
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
58
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
79
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
58
0
0
22
0
0
93
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
15
0
0
0
0
0
79
0
0
0
0
93
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
36
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
29
0
0
0
0
8
0
93
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
93
% T
% Val:
0
0
0
0
0
93
0
0
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _