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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SNAP25 All Species: 13.64
Human Site: Y101 Identified Species: 23.08
UniProt: P60880 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P60880 NP_003072.2 206 23315 Y101 K L K S S D A Y K K A W G N N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105155 211 23235 G107 K T T W G D G G E N S P C N V
Dog Lupus familis XP_859386 207 23459 Y102 K L K S S D A Y K K A W G N N
Cat Felis silvestris
Mouse Mus musculus O09044 210 23242 G106 Y K A T W G D G G D N S P S N
Rat Rattus norvegicus P60881 206 23297 Y101 K L K S S D A Y K K A W G N N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507841 243 26184 Q98 L K V S K A Y Q A V W G P G P
Chicken Gallus gallus XP_421159 209 23585 D105 A Y R T T W G D G T E N S A D
Frog Xenopus laevis NP_001080510 206 23168 Y101 K L K S S D A Y K K A W G N N
Zebra Danio Brachydanio rerio Q5TZ66 204 22839 A99 C N K M K S G A S K A W G N N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P36975 212 23667 D109 S Q S F K E D D G T W K G N D
Honey Bee Apis mellifera XP_394588 213 23546 E110 G A S F K E D E G T W K G N D
Nematode Worm Caenorhab. elegans P83351 277 31097 L140 Q S K S A S R L S E T A T N L
Sea Urchin Strong. purpuratus NP_999754 212 23995 K107 F E K G D D Y K K T W K G N D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LMG8 263 29057 I154 K N I T G P M I T P D K P S K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 60.6 94.1 N.A. 61.4 100 N.A. 57.6 59.3 95.1 93.1 N.A. 60.3 60.5 22.3 60.3
Protein Similarity: 100 N.A. 76.3 97 N.A. 77.6 100 N.A. 67.9 76.5 97 96.1 N.A. 75 74.1 38.6 74.5
P-Site Identity: 100 N.A. 20 100 N.A. 6.6 100 N.A. 6.6 0 100 46.6 N.A. 13.3 13.3 20 33.3
P-Site Similarity: 100 N.A. 33.3 100 N.A. 20 100 N.A. 6.6 26.6 100 46.6 N.A. 26.6 26.6 40 40
Percent
Protein Identity: N.A. N.A. N.A. 23.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 8 8 29 8 8 0 36 8 0 8 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 8 43 22 15 0 8 8 0 0 0 29 % D
% Glu: 0 8 0 0 0 15 0 8 8 8 8 0 0 0 0 % E
% Phe: 8 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 15 8 22 15 29 0 0 8 58 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 43 15 50 0 29 0 0 8 36 36 0 29 0 0 8 % K
% Leu: 8 29 0 0 0 0 0 8 0 0 0 0 0 0 8 % L
% Met: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 15 0 0 0 0 0 0 0 8 8 8 0 72 43 % N
% Pro: 0 0 0 0 0 8 0 0 0 8 0 8 22 0 8 % P
% Gln: 8 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 8 8 15 43 29 15 0 0 15 0 8 8 8 15 0 % S
% Thr: 0 8 8 22 8 0 0 0 8 29 8 0 8 0 0 % T
% Val: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 8 8 8 0 0 0 0 29 36 0 0 0 % W
% Tyr: 8 8 0 0 0 0 15 29 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _