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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMA6 All Species: 42.73
Human Site: S177 Identified Species: 72.31
UniProt: P60900 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P60900 NP_002782.1 246 27399 S177 V K Q T E S T S F L E K K V K
Chimpanzee Pan troglodytes XP_001139565 209 23319 G148 I G I D E E Q G P Q V Y K C D
Rhesus Macaque Macaca mulatta XP_001095366 246 27395 S177 V K Q T E S T S F L E K K V K
Dog Lupus familis XP_537412 246 27367 S177 V K Q T E S T S F L E K K V K
Cat Felis silvestris
Mouse Mus musculus Q9QUM9 246 27354 S177 V K Q T E S T S F L E K K V K
Rat Rattus norvegicus P60901 246 27381 S177 V K Q T E S T S F L E K K V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511492 246 27422 S177 V K Q T E S T S F L E K K V K
Chicken Gallus gallus XP_421242 246 27452 S177 V K Q T E S T S F L E K K V K
Frog Xenopus laevis NP_001088418 246 27318 S177 V K Q T E A T S F L E K K V K
Zebra Danio Brachydanio rerio NP_001002589 246 27351 S177 V K Q T E A T S F L E K K V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XZJ4 244 27144 A175 V G A K T L E A N S Y L E K K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17586 246 27030 S177 V K Q L P A T S F L E K K I K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81146 246 27276 N177 M K E Q E A V N F L E K K M K
Baker's Yeast Sacchar. cerevisiae P21243 252 27982 T180 P K Q Q E I T T N L E N H F K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.1 99.5 99.5 N.A. 99.5 100 N.A. 97.1 96.7 92.6 91 N.A. 66.6 N.A. 56.5 N.A.
Protein Similarity: 100 83.7 100 100 N.A. 100 100 N.A. 99.1 97.9 97.9 97.9 N.A. 80.8 N.A. 75.6 N.A.
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 100 100 93.3 93.3 N.A. 13.3 N.A. 73.3 N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 26.6 N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 64.2 54.3 N.A.
Protein Similarity: N.A. N.A. N.A. 81.7 72.2 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 29 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 8 0 86 8 8 0 0 0 86 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 79 0 0 0 0 8 0 % F
% Gly: 0 15 0 0 0 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 0 8 0 0 8 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 86 0 8 0 0 0 0 0 0 0 79 86 8 93 % K
% Leu: 0 0 0 8 0 8 0 0 0 86 0 8 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 8 15 0 0 8 0 0 0 % N
% Pro: 8 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 79 15 0 0 8 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 50 0 72 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 65 8 0 79 8 0 0 0 0 0 0 0 % T
% Val: 79 0 0 0 0 0 8 0 0 0 8 0 0 65 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _