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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMA6 All Species: 43.94
Human Site: T190 Identified Species: 74.36
UniProt: P60900 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P60900 NP_002782.1 246 27399 T190 V K K K F D W T F E Q T V E T
Chimpanzee Pan troglodytes XP_001139565 209 23319 C161 C D P A G Y Y C G F K A T A A
Rhesus Macaque Macaca mulatta XP_001095366 246 27395 T190 V K K K F D W T F E Q T V E T
Dog Lupus familis XP_537412 246 27367 T190 V K K K F D W T F E Q T V E T
Cat Felis silvestris
Mouse Mus musculus Q9QUM9 246 27354 T190 V K K K F D W T F E Q T V E T
Rat Rattus norvegicus P60901 246 27381 T190 V K K K F D W T F E Q T V E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511492 246 27422 T190 V K K K F D W T F E Q T V E T
Chicken Gallus gallus XP_421242 246 27452 T190 V K K K F D W T Y E Q T V E T
Frog Xenopus laevis NP_001088418 246 27318 T190 V K K K L D W T Y G Q T L E T
Zebra Danio Brachydanio rerio NP_001002589 246 27351 T190 V K K K L D W T F E Q A V E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XZJ4 244 27144 S188 K K Y K P N L S E E K A I Q L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17586 246 27030 T190 I K K K S E L T S T E A I E L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81146 246 27276 T190 M K E N P S F T F D E T V Q T
Baker's Yeast Sacchar. cerevisiae P21243 252 27982 H193 F K K S K I D H I N E E S W E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.1 99.5 99.5 N.A. 99.5 100 N.A. 97.1 96.7 92.6 91 N.A. 66.6 N.A. 56.5 N.A.
Protein Similarity: 100 83.7 100 100 N.A. 100 100 N.A. 99.1 97.9 97.9 97.9 N.A. 80.8 N.A. 75.6 N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 100 93.3 73.3 86.6 N.A. 20 N.A. 33.3 N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 100 100 86.6 86.6 N.A. 53.3 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 64.2 54.3 N.A.
Protein Similarity: N.A. N.A. N.A. 81.7 72.2 N.A.
P-Site Identity: N.A. N.A. N.A. 40 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 0 0 29 0 8 8 % A
% Cys: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 65 8 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 8 0 0 8 65 22 8 0 72 8 % E
% Phe: 8 0 0 0 50 0 8 0 58 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 8 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 8 0 0 8 0 0 0 15 0 0 % I
% Lys: 8 93 79 79 8 0 0 0 0 0 15 0 0 0 0 % K
% Leu: 0 0 0 0 15 0 15 0 0 0 0 0 8 0 15 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 0 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 8 0 15 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 65 0 0 15 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 8 8 8 0 8 8 0 0 0 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 79 0 8 0 65 8 0 72 % T
% Val: 65 0 0 0 0 0 0 0 0 0 0 0 65 0 0 % V
% Trp: 0 0 0 0 0 0 65 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 8 0 0 8 8 0 15 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _