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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC42
All Species:
8.79
Human Site:
T182
Identified Species:
12.89
UniProt:
P60953
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60953
NP_001034891.1
191
21311
T182
A
A
L
E
P
P
E
T
Q
P
K
R
K
C
C
Chimpanzee
Pan troglodytes
XP_001159920
191
21268
P182
A
A
L
E
P
P
E
P
K
K
S
R
R
C
V
Rhesus Macaque
Macaca mulatta
XP_001117007
191
21241
P182
A
A
L
E
P
P
E
P
K
K
S
R
R
C
V
Dog
Lupus familis
XP_849332
191
21210
P182
A
A
L
E
P
P
E
P
K
K
S
R
R
C
V
Cat
Felis silvestris
Mouse
Mus musculus
P60766
191
21292
T182
A
A
L
E
P
P
E
T
Q
P
K
R
K
C
C
Rat
Rattus norvegicus
Q6RUV5
192
21432
V182
A
V
L
C
P
P
P
V
K
K
R
K
R
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516353
201
22485
G193
C
S
A
L
T
Q
E
G
L
R
E
G
L
L
E
Chicken
Gallus gallus
Q90694
191
21254
P182
A
A
L
E
P
P
E
P
K
K
T
R
R
C
V
Frog
Xenopus laevis
NP_001079368
191
21285
P182
A
A
L
E
P
P
E
P
K
K
K
R
K
C
M
Zebra Danio
Brachydanio rerio
NP_001018130
191
21351
T182
A
A
L
E
P
P
E
T
Q
R
K
R
K
C
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40793
191
21384
P182
A
A
L
E
P
P
E
P
T
K
K
R
K
C
K
Honey Bee
Apis mellifera
XP_394608
191
21185
P182
A
A
L
E
P
P
E
P
V
K
K
R
K
C
T
Nematode Worm
Caenorhab. elegans
Q05062
191
21147
Q182
A
A
L
D
P
P
Q
Q
E
K
K
K
K
C
N
Sea Urchin
Strong. purpuratus
XP_789429
191
21304
P182
A
A
L
E
P
P
E
P
V
K
K
K
R
C
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38912
198
21710
N183
V
V
L
Q
P
P
K
N
K
K
K
K
K
R
K
Baker's Yeast
Sacchar. cerevisiae
P19073
191
21304
I182
A
A
L
E
P
P
V
I
K
K
S
K
K
C
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
94.2
94.7
N.A.
100
70.3
N.A.
84
95.2
96.3
99.4
N.A.
91.6
91
86.3
88.4
Protein Similarity:
100
96.8
96.8
96.8
N.A.
100
81.2
N.A.
84.5
97.3
97.9
99.4
N.A.
94.2
95.2
94.7
94.2
P-Site Identity:
100
60
60
60
N.A.
100
33.3
N.A.
6.6
60
73.3
93.3
N.A.
73.3
73.3
53.3
60
P-Site Similarity:
100
73.3
73.3
73.3
N.A.
100
60
N.A.
20
73.3
80
93.3
N.A.
73.3
73.3
80
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
54
79.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.1
87.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
88
82
7
0
0
0
0
0
0
0
0
0
0
0
7
% A
% Cys:
7
0
0
7
0
0
0
0
0
0
0
0
0
82
25
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
75
0
0
75
0
7
0
7
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
7
0
50
75
57
32
57
7
13
% K
% Leu:
0
0
94
7
0
0
0
0
7
0
0
0
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
94
94
7
50
0
13
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
7
7
7
19
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
13
7
63
38
7
7
% R
% Ser:
0
7
0
0
0
0
0
0
0
0
25
0
0
0
0
% S
% Thr:
0
0
0
0
7
0
0
19
7
0
7
0
0
0
7
% T
% Val:
7
13
0
0
0
0
7
7
13
0
0
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _