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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC42
All Species:
59.7
Human Site:
Y154
Identified Species:
87.56
UniProt:
P60953
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60953
NP_001034891.1
191
21311
Y154
R
D
L
K
A
V
K
Y
V
E
C
S
A
L
T
Chimpanzee
Pan troglodytes
XP_001159920
191
21268
Y154
R
D
L
K
A
V
K
Y
V
E
C
S
V
L
T
Rhesus Macaque
Macaca mulatta
XP_001117007
191
21241
Y154
R
D
L
K
A
V
R
Y
V
E
C
S
A
L
T
Dog
Lupus familis
XP_849332
191
21210
Y154
R
D
L
K
A
V
K
Y
V
E
C
S
A
L
T
Cat
Felis silvestris
Mouse
Mus musculus
P60766
191
21292
Y154
R
D
L
K
A
V
K
Y
V
E
C
S
A
L
T
Rat
Rattus norvegicus
Q6RUV5
192
21432
Y154
K
E
I
G
A
V
K
Y
L
E
C
S
A
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516353
201
22485
T170
Q
K
P
I
T
P
E
T
A
E
K
L
A
R
D
Chicken
Gallus gallus
Q90694
191
21254
Y154
R
D
L
K
A
V
K
Y
V
E
C
S
A
L
T
Frog
Xenopus laevis
NP_001079368
191
21285
Y154
R
D
L
K
A
V
K
Y
V
E
C
S
A
L
T
Zebra Danio
Brachydanio rerio
NP_001018130
191
21351
Y154
R
D
L
K
A
V
K
Y
V
E
C
S
A
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40793
191
21384
Y154
K
E
L
K
A
V
K
Y
V
E
C
S
A
L
T
Honey Bee
Apis mellifera
XP_394608
191
21185
Y154
K
E
L
K
A
V
K
Y
V
E
C
S
A
L
T
Nematode Worm
Caenorhab. elegans
Q05062
191
21147
Y154
K
E
L
K
A
V
K
Y
V
E
C
S
A
L
T
Sea Urchin
Strong. purpuratus
XP_789429
191
21304
Y154
K
E
L
R
A
V
K
Y
V
E
C
S
A
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38912
198
21710
E157
I
G
A
P
A
Y
I
E
C
S
A
K
T
Q
Q
Baker's Yeast
Sacchar. cerevisiae
P19073
191
21304
Y154
R
E
L
K
A
V
K
Y
V
E
C
S
A
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
94.2
94.7
N.A.
100
70.3
N.A.
84
95.2
96.3
99.4
N.A.
91.6
91
86.3
88.4
Protein Similarity:
100
96.8
96.8
96.8
N.A.
100
81.2
N.A.
84.5
97.3
97.9
99.4
N.A.
94.2
95.2
94.7
94.2
P-Site Identity:
100
93.3
93.3
100
N.A.
100
66.6
N.A.
13.3
100
100
100
N.A.
86.6
86.6
86.6
80
P-Site Similarity:
100
93.3
100
100
N.A.
100
93.3
N.A.
26.6
100
100
100
N.A.
100
100
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
54
79.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.1
87.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
93.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
94
0
0
0
7
0
7
0
88
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
88
0
0
0
0
% C
% Asp:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
7
% D
% Glu:
0
38
0
0
0
0
7
7
0
94
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
7
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
32
7
0
75
0
0
82
0
0
0
7
7
0
0
0
% K
% Leu:
0
0
82
0
0
0
0
0
7
0
0
7
0
88
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
7
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% Q
% Arg:
57
0
0
7
0
0
7
0
0
0
0
0
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
0
88
0
0
0
% S
% Thr:
0
0
0
0
7
0
0
7
0
0
0
0
7
0
88
% T
% Val:
0
0
0
0
0
88
0
0
82
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
88
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _