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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC42 All Species: 62.42
Human Site: Y32 Identified Species: 91.56
UniProt: P60953 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P60953 NP_001034891.1 191 21311 Y32 T N K F P S E Y V P T V F D N
Chimpanzee Pan troglodytes XP_001159920 191 21268 Y32 T N K F P S E Y V P T V F D N
Rhesus Macaque Macaca mulatta XP_001117007 191 21241 Y32 T N K F P S E Y V P T V F D N
Dog Lupus familis XP_849332 191 21210 Y32 T N K F P S E Y V P A V F D N
Cat Felis silvestris
Mouse Mus musculus P60766 191 21292 Y32 T N K F P S E Y V P T V F D N
Rat Rattus norvegicus Q6RUV5 192 21432 Y32 T N A F P G E Y I P T V F D N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516353 201 22485 L48 G A V G K T C L L I S Y T T N
Chicken Gallus gallus Q90694 191 21254 Y32 T N K F P S E Y V P T V F D N
Frog Xenopus laevis NP_001079368 191 21285 Y32 T N K F P S E Y V P T V F D N
Zebra Danio Brachydanio rerio NP_001018130 191 21351 Y32 T N K F P S E Y V P T V F D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40793 191 21384 Y32 T N K F P S E Y V P T V F D N
Honey Bee Apis mellifera XP_394608 191 21185 Y32 T N K F P S E Y V P T V F D N
Nematode Worm Caenorhab. elegans Q05062 191 21147 Y32 T N K F P S E Y V P T V F D N
Sea Urchin Strong. purpuratus XP_789429 191 21304 Y32 T N K F P S E Y V P T V F D N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38912 198 21710 Y35 S N T F P T D Y V P T V F D N
Baker's Yeast Sacchar. cerevisiae P19073 191 21304 Y32 T N Q F P A D Y V P T V F D N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 94.2 94.7 N.A. 100 70.3 N.A. 84 95.2 96.3 99.4 N.A. 91.6 91 86.3 88.4
Protein Similarity: 100 96.8 96.8 96.8 N.A. 100 81.2 N.A. 84.5 97.3 97.9 99.4 N.A. 94.2 95.2 94.7 94.2
P-Site Identity: 100 100 100 93.3 N.A. 100 80 N.A. 6.6 100 100 100 N.A. 100 100 100 100
P-Site Similarity: 100 100 100 93.3 N.A. 100 86.6 N.A. 26.6 100 100 100 N.A. 100 100 100 100
Percent
Protein Identity: N.A. N.A. N.A. 54 79.5 N.A.
Protein Similarity: N.A. N.A. N.A. 69.1 87.4 N.A.
P-Site Identity: N.A. N.A. N.A. 73.3 80 N.A.
P-Site Similarity: N.A. N.A. N.A. 93.3 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 0 7 0 0 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 13 0 0 0 0 0 0 94 0 % D
% Glu: 0 0 0 0 0 0 82 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 94 0 0 0 0 0 0 0 0 94 0 0 % F
% Gly: 7 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % I
% Lys: 0 0 75 0 7 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 94 0 0 0 0 0 0 0 0 0 0 0 0 100 % N
% Pro: 0 0 0 0 94 0 0 0 0 94 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 7 0 0 0 0 75 0 0 0 0 7 0 0 0 0 % S
% Thr: 88 0 7 0 0 13 0 0 0 0 88 0 7 7 0 % T
% Val: 0 0 7 0 0 0 0 0 88 0 0 94 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 94 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _