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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DSTN
All Species:
39.7
Human Site:
T25
Identified Species:
67.18
UniProt:
P60981
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60981
NP_001011546.1
165
18506
T25
M
K
V
R
K
C
S
T
P
E
E
I
K
K
R
Chimpanzee
Pan troglodytes
XP_514526
257
28197
T117
M
K
V
R
K
C
S
T
P
E
E
I
K
K
R
Rhesus Macaque
Macaca mulatta
XP_001118077
454
48753
T313
M
K
V
R
K
S
S
T
P
E
E
V
K
K
R
Dog
Lupus familis
XP_534337
181
20333
T41
M
K
V
R
K
C
S
T
P
E
E
I
K
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0P5
165
18503
T25
M
K
V
R
K
C
S
T
P
E
E
I
K
K
R
Rat
Rattus norvegicus
Q7M0E3
165
18515
T25
M
K
V
R
K
C
S
T
P
E
E
I
K
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515434
218
24382
T78
M
K
V
R
K
C
S
T
P
E
E
I
K
K
R
Chicken
Gallus gallus
P18359
165
18514
T25
M
K
V
R
K
C
S
T
P
E
E
V
K
K
R
Frog
Xenopus laevis
Q5XHH8
167
18839
T25
M
K
V
R
K
S
S
T
P
E
E
I
K
K
R
Zebra Danio
Brachydanio rerio
NP_991263
166
18550
S25
M
K
V
R
K
S
S
S
S
D
E
V
K
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P45594
148
17135
R25
I
K
K
D
K
K
H
R
Y
V
I
F
Y
I
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43694
139
16065
R28
L
K
A
R
R
S
F
R
F
I
V
F
R
I
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZSK2
146
16689
L26
D
E
S
K
T
T
F
L
E
L
Q
R
K
K
T
Baker's Yeast
Sacchar. cerevisiae
Q03048
143
15882
K26
L
K
L
G
K
K
Y
K
F
I
L
F
G
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
26.8
91.1
N.A.
95.7
95.7
N.A.
75.2
95.1
67
66.8
N.A.
32.1
N.A.
N.A.
N.A.
Protein Similarity:
100
64.1
31.7
91.1
N.A.
96.3
96.3
N.A.
75.2
97.5
82
84.3
N.A.
52.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
100
N.A.
100
100
N.A.
100
93.3
93.3
66.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
100
93.3
86.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
28.4
N.A.
29
33.9
N.A.
Protein Similarity:
N.A.
46.6
N.A.
52.7
51.5
N.A.
P-Site Identity:
N.A.
13.3
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% D
% Glu:
0
8
0
0
0
0
0
0
8
65
72
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
15
0
15
0
0
22
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
15
8
50
0
15
0
% I
% Lys:
0
93
8
8
86
15
0
8
0
0
0
0
79
79
0
% K
% Leu:
15
0
8
0
0
0
0
8
0
8
8
0
0
8
0
% L
% Met:
72
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
65
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
79
8
0
0
15
0
0
0
8
8
0
79
% R
% Ser:
0
0
8
0
0
29
72
8
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
8
0
65
0
0
0
0
0
0
8
% T
% Val:
0
0
72
0
0
0
0
0
0
8
8
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _