KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAB8A
All Species:
26.97
Human Site:
S185
Identified Species:
42.38
UniProt:
P61006
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61006
NP_005361.2
207
23668
S185
E
G
N
S
P
Q
G
S
N
Q
G
V
K
I
T
Chimpanzee
Pan troglodytes
XP_524147
772
86340
S397
E
G
N
S
P
Q
G
S
N
Q
G
V
K
I
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P55258
207
23650
S185
E
G
N
S
P
Q
G
S
S
H
G
V
K
I
T
Rat
Rattus norvegicus
P70550
207
23585
A185
N
D
S
N
S
S
G
A
G
G
P
V
K
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520827
219
24637
S197
E
G
N
S
P
Q
G
S
N
H
G
V
R
I
T
Chicken
Gallus gallus
Q5F470
207
23503
S185
E
G
N
S
P
Q
G
S
N
Q
G
V
K
I
T
Frog
Xenopus laevis
NP_001087181
207
23589
G185
N
E
N
V
S
P
G
G
G
G
P
V
K
I
T
Zebra Danio
Brachydanio rerio
NP_001083031
207
23556
S185
E
G
N
N
P
Q
G
S
N
H
G
V
K
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524172
207
23673
G185
E
A
N
N
P
P
K
G
G
H
Q
L
K
P
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491199
211
24004
T187
A
G
G
S
V
S
N
T
G
R
V
N
V
G
G
Sea Urchin
Strong. purpuratus
NP_001116975
207
23545
S185
D
A
T
G
Q
Q
K
S
G
G
V
K
V
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q05737
203
22457
N181
A
S
Q
P
A
A
A
N
A
R
P
A
T
V
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P28186
216
23816
T192
D
S
R
A
E
P
A
T
I
K
I
S
Q
T
D
Baker's Yeast
Sacchar. cerevisiae
P07560
215
23487
N194
N
K
L
V
G
V
G
N
G
K
E
G
N
I
S
Red Bread Mold
Neurospora crassa
P33723
203
22458
T182
S
S
I
A
T
N
N
T
K
A
S
V
N
V
S
Conservation
Percent
Protein Identity:
100
24.2
N.A.
N.A.
N.A.
97
82.6
N.A.
78
93.7
82.6
93.2
N.A.
79.2
N.A.
71
83
Protein Similarity:
100
25.9
N.A.
N.A.
N.A.
98.5
92.7
N.A.
82.6
97.5
91.7
97.5
N.A.
88.4
N.A.
87.1
92.7
P-Site Identity:
100
100
N.A.
N.A.
N.A.
86.6
33.3
N.A.
86.6
100
40
86.6
N.A.
26.6
N.A.
13.3
13.3
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
93.3
53.3
N.A.
93.3
100
40
93.3
N.A.
40
N.A.
26.6
20
Percent
Protein Identity:
N.A.
50.7
N.A.
58.3
51.1
52.6
Protein Similarity:
N.A.
71
N.A.
72.2
70.7
69.5
P-Site Identity:
N.A.
0
N.A.
0
13.3
6.6
P-Site Similarity:
N.A.
20
N.A.
33.3
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
0
14
7
7
14
7
7
7
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% D
% Glu:
47
7
0
0
7
0
0
0
0
0
7
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
47
7
7
7
0
60
14
40
20
40
7
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
27
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
7
0
7
0
0
60
0
% I
% Lys:
0
7
0
0
0
0
14
0
7
14
0
7
54
0
0
% K
% Leu:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
20
0
54
20
0
7
14
14
34
0
0
7
14
0
0
% N
% Pro:
0
0
0
7
47
20
0
0
0
0
20
0
0
7
0
% P
% Gln:
0
0
7
0
7
47
0
0
0
20
7
0
7
0
7
% Q
% Arg:
0
0
7
0
0
0
0
0
0
14
0
0
7
0
0
% R
% Ser:
7
20
7
40
14
14
0
47
7
0
7
7
0
0
14
% S
% Thr:
0
0
7
0
7
0
0
20
0
0
0
0
7
14
54
% T
% Val:
0
0
0
14
7
7
0
0
0
0
14
60
14
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _